期刊
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
卷 24, 期 -, 页码 -出版社
JOHN WILEY & SONS LTD
DOI: 10.1002/jia2.25808
关键词
antiretroviral treatment; COVID-19; differentiated service delivery; HIV service delivery; multi-month dispensing; Zambia
资金
- Bill & Melinda Gates Foundation [OPP1192640]
- Ruth L. Kirschstein National Research Service Award ,National Institutes of Health T32 Training Grant [T32 AI052074-14]
- Bill and Melinda Gates Foundation [OPP1192640] Funding Source: Bill and Melinda Gates Foundation
In Zambia, participation in DSD models for stable ART clients increased during the COVID-19 pandemic, however, dispensing intervals decreased. Eliminating obstacles related to supply chain management is essential to achieve the expected benefits of DSD models and minimize COVID-19 risk.
Introduction Differentiated service delivery (DSD) models aim to improve the access of human immunodeficiency virus treatment on clients and reduce requirements for facility visits by extending dispensing intervals. With the advent of the COVID-19 pandemic, minimising client contact with healthcare facilities and other clients, while maintaining treatment continuity and avoiding loss to care, has become more urgent, resulting in efforts to increase DSD uptake. We assessed the extent to which DSD coverage and antiretroviral treatment (ART) dispensing intervals have changed during the COVID-19 pandemic in Zambia. Methods We used client data from Zambia's electronic medical record system (SmartCare) for 737 health facilities, representing about three-fourths of all ART clients nationally. We compared the numbers and proportional distributions of clients enrolled in DSD models in the 6 months before and 6 months after the first case of COVID-19 was diagnosed in Zambia in March 2020. Segmented linear regression was used to determine whether the outbreak of COVID-19 in Zambia further accelerated the increase in DSD scale-up. Results and discussion Between September 2019 and August 2020, 181,317 clients aged 15 or older (81,520 and 99,797 from 1 September 2019 to 1 March 2020 and from 1 March to 31 August 2020, respectively) enrolled in DSD models in Zambia. Overall participation in all DSD models increased over the study period, but uptake varied by model. The rate of acceleration increased in the second period for home ART delivery (152%), <= 2-month fast-track (143%) and 3-month MMD (139%). There was a significant reduction in the enrolment rates for 4- to 6-month fast-track (-28%) and other models (-19%). Conclusions Participation in DSD models for stable ART clients in Zambia increased after the advent of COVID-19, but dispensing intervals diminished. Eliminating obstacles to longer dispensing intervals, including those related to supply chain management, should be prioritized to achieve the expected benefits of DSD models and minimize COVID-19 risk.
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