期刊
ACS CATALYSIS
卷 11, 期 21, 页码 13217-13222出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.1c04183
关键词
difunctionalization; isocyanide; radical; palladium; light-induced
资金
- National Institutes of Health [GM120281]
- National Science Foundation [CHE-1955663]
- Welch Foundation [AT-0041]
A novel reaction method has been developed for visible light-induced alkyl-carbamoylation and cyanation of alkenes, leading to the synthesis of amides and nitriles. This method is highly efficient and versatile, allowing for the rapid construction of a wide range of valuable compounds.
A mild visible-light-induced Pd-catalyzed one-pot three-component alkyl-carbamoylation and cyanation of alkenes was developed. This general transformation, which proceeds via the in situ formation of a reactive ketenimine intermediate, allows for a rapid construction of a broad range of valuable amides and nitriles from readily available alkenes, alkyl iodides, and isocyanides. An efficient synthesis of tetrazole and amidine via this approach was also demonstrated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据