4.8 Article

The barley immune receptor Mla recognizes multiple pathogens and contributes to host range dynamics

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Summary: Barley powdery mildew caused by the fungus Blumeria graminis forma specialis hordei (Bgh) can lead to annual yield losses of 15% in this cereal crop. Host plants have evolved a variety of disease resistance genes in response to diverse effector molecules secreted by Bgh to modify the immune status and physiology of the host. Among these genes, the Mla resistance gene has undergone diversification in the host population and plays a key role in providing isolate-specific immunity against Bgh.

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