4.8 Article

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

m6A RNA methylation regulates the fate of endogenous retroviruses

Tomasz Chelmicki et al.

Summary: Research indicates that m(6)A RNA methylation can restrict ERVs, maintaining cellular integrity by reducing the half-life of IAP mRNA to clear reactive ERV-derived RNA species.

NATURE (2021)

Article Biochemistry & Molecular Biology

Dnmt1 has de novo activity targeted to transposable elements

Chuck Haggerty et al.

Summary: Dnmt1 demonstrates de novo methylation activity with specific targeting towards retrotransposons, depending on Uhrf1. Its genomic recruitment overlaps with regions enriched for Uhrf1, Trim28, and H3K9 trimethylation. These findings suggest that Dnmt1 can catalyze DNA methylation in both de novo and maintenance contexts, particularly at retrotransposons.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)

Article Multidisciplinary Sciences

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo

Amanda R. Wasylishen et al.

SCIENCE ADVANCES (2020)

Article Multidisciplinary Sciences

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Ozgen Deniz et al.

NATURE COMMUNICATIONS (2020)

Article Genetics & Heredity

Transposable elements drive widespread expression of oncogenes in human cancers

Hyo Sik Jang et al.

NATURE GENETICS (2019)

Article Multidisciplinary Sciences

Mechanism for autoinhibition and activation of the MORC3 ATPase

Yi Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells

Parysatis Sachs et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

MORC3 Is a Target of the Influenza A Viral Protein NS1

Yi Zhang et al.

STRUCTURE (2019)

Article Biochemistry & Molecular Biology

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells

Kei Fukuda et al.

GENOME RESEARCH (2018)

Review Biochemistry & Molecular Biology

Human Endogenous Retroviruses in Neurological Diseases

Patrick Kuery et al.

TRENDS IN MOLECULAR MEDICINE (2018)

Review Cell Biology

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Guoju Hong et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2017)

Letter Multidisciplinary Sciences

On the role of H3.3 in retroviral silencing

Gernot Wolf et al.

NATURE (2017)

Article Genetics & Heredity

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2

Iva A. Tchasovnikarova et al.

NATURE GENETICS (2017)

Article Biochemical Research Methods

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

M. Ryan Corces et al.

NATURE METHODS (2017)

Article Multidisciplinary Sciences

Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX

Dominik Hoelper et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Silencing of endogenous retroviruses by heterochromatin

Sophia Groh et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Review Biochemistry & Molecular Biology

Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire

Peter J. Thompson et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin

Sisi Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Genetics & Heredity

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

Justin S. Becker et al.

TRENDS IN GENETICS (2016)

Review Genetics & Heredity

Endogenous retroviral promoter exaptation in human cancer

Artem Babaian et al.

MOBILE DNA (2016)

Article Biochemistry & Molecular Biology

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

Bin Xia Yang et al.

Article Biochemistry & Molecular Biology

Atrx promotes heterochromatin formation at retrotransposons

Dennis Sadic et al.

EMBO REPORTS (2015)

Article Multidisciplinary Sciences

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

Simon J. Elsasser et al.

NATURE (2015)

Article Biotechnology & Applied Microbiology

Transcriptional landscape of repetitive elements in normal and cancer human cells

Steven W. Criscione et al.

BMC GENOMICS (2014)

Article Biochemistry & Molecular Biology

Widespread contribution of transposable elements to the innovation of gene regulatory networks

Vasavi Sundaram et al.

GENOME RESEARCH (2014)

Letter Biochemical Research Methods

Improved vectors and genome-wide libraries for CRISPR screening

Neville E. Sanjana et al.

NATURE METHODS (2014)

Article Multidisciplinary Sciences

MORC1 represses transposable elements in the mouse male germline

William A. Pastor et al.

NATURE COMMUNICATIONS (2014)

Article Genetics & Heredity

The Majority of Primate-Specific Regulatory Sequences Are Derived from Transposable Elements

Pierre-Etienne Jacques et al.

PLOS GENETICS (2013)

Article Cell Biology

Two-step colocalization of MORC3 with PML nuclear bodies

Yasuhiro Mimura et al.

JOURNAL OF CELL SCIENCE (2010)

Article Biochemical Research Methods

A rapid micro chromatin immunoprecipitation assay (mu ChIP)

John Arne Dahl et al.

NATURE PROTOCOLS (2008)

Article Biochemistry & Molecular Biology

Core transcriptional regulatory circuitry in human embryonic stem cells

LA Boyer et al.