期刊
REVIEWS IN AQUACULTURE
卷 14, 期 2, 页码 1028-1045出版社
WILEY
DOI: 10.1111/raq.12639
关键词
antibiotic-resistance genes; aquaculture environment; human health; metal resistance genes; microorganisms; microplastics
类别
资金
- Innovation Group Project of Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) [311021006]
- National Natural Science Foundation of China [42077364]
- Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme
- National Key Research and Development Program of China [2018YFD0900604]
- Key Research Projects of Universities in Guangdong Province [2019KZDXM003, 2020KZDZX1040]
Microplastics, antibiotics, and heavy metals in aquaculture environments have serious ecological and human health consequences. Microorganisms develop antibiotic resistance genes and metal resistance genes as a defense mechanism. Heavy metals may lead bacteria to employ antibiotic resistance, while microplastics could act as potential carriers of multidrug-resistant genes.
Microplastics (MPs), antibiotics and heavy metals unavoidably contaminate the aquaculture environment, with serious ecological and human health consequences. Antibiotic-resistance genes (ARGs) and metal resistance genes (MRGs) are induced in microorganisms in the environment as a defence mechanism against antibiotics and heavy metals respectively. Furthermore, heavy metals in the aquaculture environment will cause bacteria to employ antibiotic resistance through co-selection (co-resistance or cross-resistance) and other potential mechanisms. MPs may also act as potential carriers of multidrug resistance in aquaculture environments because they are hotspots for the enrichment and transmission of antibiotic resistance. Multidrug-resistant (MDR) microorganisms in the aquaculture environment may infiltrate aquatic organisms via the food chain (eg MDR-microorganisms -> myctophids -> tuna/ squid/ whales/ seabirds/ seals), and after long-term enrichment, they may gain access to the human body, posing a major risk to aquaculture and human health. As a result, this review article summarises contamination of MPs, heavy metal and antibiotics in global aquaculture settings; discusses the generation of ARGs, MRGs and common selection mechanisms for resistance development and emphasises the role of MPs as hot spots for antibiotic-resistance selective enrichment, as well as potential carriers of multi-drug-resistant genes (MDRGs), in the aquaculture environment, posing an increasing threat to aquaculture and even human health.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据