相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A RAC-GEF network critical for early intestinal tumourigenesis
K. A. Pickering et al.
NATURE COMMUNICATIONS (2021)
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
Victoria Gudino et al.
NATURE COMMUNICATIONS (2021)
RAC1B Induces SMAD7 via USP26 to Suppress TGFβ1-Dependent Cell Migration in Mesenchymal-Subtype Carcinoma Cells
Hendrik Ungefroren et al.
CANCERS (2020)
The Small GTPase RAC1B: A Potent Negative Regulator of-and Useful Tool to Study-TGFβ Signaling
Hendrik Ungefroren et al.
CANCERS (2020)
Transforming Growth Factor-β Signaling in Immunity and Cancer
Eduard Batlle et al.
IMMUNITY (2019)
RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5
Hendrik Ungefroren et al.
CANCERS (2019)
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis
Max D. Wellenstein et al.
NATURE (2019)
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
Rene Jackstadt et al.
CANCER CELL (2019)
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Francisco Sanchez-Vega et al.
CELL (2018)
Contextual determinants of TGFβ action in development, immunity and cancer
Charles J. David et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression
Larissa Kotelevets et al.
ONCOGENE (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma
Bin Dai et al.
CELL COMMUNICATION AND SIGNALING (2018)
Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer
Barbara Jung et al.
GASTROENTEROLOGY (2017)
Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation
M. Nakayama et al.
ONCOGENE (2017)
Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b
David Witte et al.
SCIENTIFIC REPORTS (2017)
The Rac GTPase in Cancer: From Old Concepts to New Paradigms
Marcelo G. Kazanietz et al.
CANCER RESEARCH (2017)
The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma
Catharina Melzer et al.
CELL COMMUNICATION AND SIGNALING (2017)
TCGASpliceSeq a compendium of alternative mRNA splicing in cancer.
Michael Ryan et al.
NUCLEIC ACIDS RESEARCH (2016)
Regulating Rho GTPases and their regulators
Richard G. Hodge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β
Zoltan Wiener et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
T. Grabinger et al.
CELL DEATH & DISEASE (2014)
Rac1b negatively regulates TGF-beta 1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling
Hendrik Ungefroren et al.
ONCOTARGET (2014)
Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors
Sarah Schwitalla et al.
CANCER CELL (2013)
ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation
Kevin B. Myant et al.
CELL STEM CELL (2013)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis
C. Zhou et al.
ONCOGENE (2013)
Involvement of hnRNP A1 in the Matrix Metalloprotease-3-Dependent Regulation of Rac1 Pre-mRNA Splicing
Federico Pelisch et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression
Melody L. Stallings-Mann et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling
Nam Hee Kim et al.
SCIENCE SIGNALING (2011)
Transforming growth factor beta (TGF beta)-induced apoptosis The rise & fall of Bim
Sneha Ramesh et al.
CELL CYCLE (2009)
Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
Susmita Esufali et al.
CANCER RESEARCH (2007)
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
DC Radisky et al.
NATURE (2005)
Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase
D Fiegen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
F El Marjou et al.
GENESIS (2004)
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
J Jonkers et al.
NATURE GENETICS (2001)
Small GTPase Rac1:: Structure, localization, and expression of the human gene
P Matos et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b
A Schnelzer et al.
ONCOGENE (2000)