4.7 Article

BET protein inhibition evidently enhances sensitivity to PI3K/mTOR dual inhibition in intrahepatic cholangiocarcinoma

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Plant Sciences

Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway

Shuo Wang et al.

Summary: The chloroform extract of Sophora tonkinensis Gagnep. (CESTG) has shown anticancer effects on nasopharyngeal carcinoma (NPC) by inhibiting cell proliferation, clonal growth, and inducing apoptosis in a dose-dependent manner through the PI3K/AKT/mTOR signaling pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Cell Biology

Targeting Wnt/β-catenin and PI3K/Akt/mTOR pathways in T-cell acute lymphoblastic leukemia

Cecilia Evangelisti et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Review Oncology

Targeting mTOR for cancer therapy

Hui Hua et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

Review Oncology

YAP/TAZ Signaling and Resistance to Cancer Therapy

Chan D. K. Nguyen et al.

TRENDS IN CANCER (2019)

Article Multidisciplinary Sciences

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Tyler Risom et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Vasculogenic mimicry formation in EBV-associated epithelial malignancies

Tong Xiang et al.

NATURE COMMUNICATIONS (2018)

Review Biochemistry & Molecular Biology

PIM Kinases and Their Relevance to the PI3K/AKT/mTOR Pathway in the Regulation of Ovarian Cancer

Aziz Ur Rehman Aziz et al.

BIOMOLECULES (2018)

Article Biochemistry & Molecular Biology

The BET Bromodomain Inhibitor JQ1 Suppresses Chondrosarcoma Cell Growth via Regulation of YAP/p21/c-Myc Signaling

Huan-Tian Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

Article Gastroenterology & Hepatology

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice

Shanshan Zhang et al.

JOURNAL OF HEPATOLOGY (2017)

Article Multidisciplinary Sciences

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Zhipeng Meng et al.

NATURE COMMUNICATIONS (2015)

Article Oncology

Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC

Susan Heavey et al.

CANCER BIOLOGY & THERAPY (2014)

Review Oncology

Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC

Susan Heavey et al.

CANCER TREATMENT REVIEWS (2014)

Article Gastroenterology & Hepatology

Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

John Bridgewater et al.

JOURNAL OF HEPATOLOGY (2014)

Review Biochemistry & Molecular Biology

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition

Junwei Shi et al.

MOLECULAR CELL (2014)

Review Oncology

Targeting PI3K/Akt/mTOR signaling in cancer

Camillo Porta et al.

FRONTIERS IN ONCOLOGY (2014)

Review Oncology

Development of PI3K inhibitors: lessons learned from early clinical trials

Jordi Rodon et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2013)

Article Developmental Biology

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP

Katrin Strassburger et al.

DEVELOPMENTAL BIOLOGY (2012)

Article Developmental Biology

Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila

Xin Ye et al.

DEVELOPMENTAL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake E. Delmore et al.

Review Gastroenterology & Hepatology

Clinical diagnosis and staging of cholangiocarcinoma

Boris Blechacz et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)

Review Oncology

Targeting hypoxia in cancer therapy

William R. Wilson et al.

NATURE REVIEWS CANCER (2011)

Article Multidisciplinary Sciences

Selective inhibition of BET bromodomains

Panagis Filippakopoulos et al.

NATURE (2010)

Review Biochemistry & Molecular Biology

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

M. N. Corradetti et al.

ONCOGENE (2006)

Review Medicine, General & Internal

Cholangiocarcinoma

SA Khan et al.

LANCET (2005)

Article Multidisciplinary Sciences

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

DD Sarbassov et al.

SCIENCE (2005)