期刊
HPB
卷 24, 期 5, 页码 772-781出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.hpb.2021.09.025
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Universitary Department; H?pital Beaujon; 100 boulevard du General Leclerc; 92110; Clichy; France
This study reported the incidence of delayed gastric emptying (DGE) following elective distal pancreatectomy (DP) and identified age, surgical approach, and postoperative pancreatic fistula (POPF) grade B-C as predisposing factors for DGE. DGE significantly increased the length of hospital stay. The study suggests that laparoscopic approach and prevention of POPF should be encouraged to reduce the incidence of DGE.
Background: Delayed gastric emptying (DGE) following elective distal pancreatectomy (DP) is poorly known. This study aimed to report incidence of DGE following DP, to identify its predisposing factors, and to assess its impact on hospital stay. Methods: Patients who had elective DP without additional organ or vascular resection (2012-2017) in two academic hospitals were included. Factors predisposing to DGE, defined according to the International Study Group of Pancreatic Surgery, were identified by multivariate analysis. A systematic review was performed to evaluate DGE incidence following elective DP. Results: 311 elective DPs were performed. Three perioperative mortalities (1.0%) were unrelated to DGE. DGE occurred in 31 (10.0%) patients (grade A = 21, grade B = 7, grade C = 3) with a median hospital stay of 16 (13-22) days versus 10 (7-14) without DGE (p < 0.001). In multivariate analysis, predisposing factors of DGE were age > 75 years (OR = 4.32 [1.53-12.19]; p = 0.006), open approach (OR = 2.97 [1.1-8]; p = 0.031) and POPF grade B-C (OR = 2.54 [1.05-6.1]; p = 0.038). The systematic review identified 7 series including 876 patients with an overall 8.1% DGE incidence. Conclusion: DGE complicates around 10% of elective DP. Laparoscopic approach and prevention of POPF should be encouraged to reduce DGE incidence.
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