4.6 Review

Modes of Brain Cell Death Following Intracerebral Hemorrhage

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Clinical Neurology

Effect of Deferoxamine on Outcome According to Baseline Hematoma Volume: A Post Hoc Analysis of the i-DEF Trial

Chenchen Wei et al.

Summary: This study found that among patients with moderate hematoma volume, a greater proportion of deferoxamine-treated patients achieved modified Rankin Scale score 0-2. The treatment effect was not significant for small or large hematoma volumes. These findings have important implications for trial design and therapeutic approaches.

STROKE (2022)

Review Biology

Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage

Yan Zhang et al.

Summary: Intracerebral hemorrhage (ICH) is a devastating disease that affects approximately 2 million patients worldwide annually. This review focuses on understanding the pathological roles of gap junctions and hemichannels in secondary brain injury following ICH, with the aim of identifying effective therapeutic strategies for ICH.

BIOLOGY-BASEL (2022)

Article Clinical Neurology

Metformin Ameliorates Neuronal Necroptosis after Intracerebral Hemor-rhage by Activating AMPK

Chenhan Lin et al.

Summary: The study found that metformin can effectively inhibit neuronal necroptosis after ICH by activating the AMPK related pathway, resulting in significant improvements in neurological function scores and reduction in brain edema.

CURRENT NEUROVASCULAR RESEARCH (2021)

Article Endocrinology & Metabolism

Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice

Sevda Lule et al.

Summary: RIPK1 plays a central role in the pathogenesis of intracerebral hemorrhage by regulating cell death, edema, blood-brain barrier permeability, and motor deficits, potentially through the activation of MLKL-dependent necroptosis.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2021)

Article Neurosciences

Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice

Yang Liu et al.

Summary: The study demonstrates that minocycline plays a protective role in ICH by reducing EMMPRIN and MMP-9 expression, alleviating BBB disruption, inhibiting neuroinflammation, and decreasing neuronal degeneration and death.

NEUROSCIENCE LETTERS (2021)

Article Biochemistry & Molecular Biology

Activated Microglia Exosomes Mediated miR-383-3p Promotes Neuronal Necroptosis Through Inhibiting ATF4 Expression in Intracerebral Hemorrhage

Min Wei et al.

Summary: Intracerebral hemorrhage (ICH) is a severe condition with high mortality and morbidity, where secondary brain injury plays a key role. The involvement of exosomes and miRNAs in this process is significant, particularly in the regulation of neuronal necroptosis. Further research is needed to fully understand these mechanisms and potentially develop new strategies for treating ICH.

NEUROCHEMICAL RESEARCH (2021)

Article Clinical Neurology

The combination of deferoxamine and minocycline strengthens neuroprotective effect on acute intracerebral hemorrhage in rats

Zhe Li et al.

Summary: The combination therapy of deferoxamine and minocycline showed promising results in reducing iron accumulation, neuronal death, and inflammation in an adult rat model of intracerebral hemorrhage. Additionally, the combination treatment demonstrated better outcomes in neuroprotection and anti-inflammatory effects compared to monotherapy. The study suggests that this combinational therapy could be a potential therapeutic option for treating ICH.

NEUROLOGICAL RESEARCH (2021)

Article Oncology

Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage

Jianyang Liu et al.

Summary: This study showed that hypoxic preconditioning could enhance the therapeutic effects of OM-MSCs, alleviating microglial pyroptosis in ICH model by reducing inflammatory responses and regulating pyroptosis-related proteins. Hypoxia-preconditioned OM-MSCs significantly improved functional recovery and reduced neuronal injury in ICH mice, indicating a potential neuroprotective strategy for ICH treatment.

ANNALS OF TRANSLATIONAL MEDICINE (2021)

Review Clinical Neurology

Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets

Christine Tschoe et al.

JOURNAL OF STROKE (2020)

Review Clinical Neurology

Intracerebral haemorrhage: from clinical settings to animal models

Qian Bai et al.

STROKE AND VASCULAR NEUROLOGY (2020)

Review Medicine, Research & Experimental

The emerging role of ferroptosis in inflammation

Yitian Sun et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Clinical Neurology

Clinical diagnostic and therapeutic guidelines of stroke neurorestoration (2020 China version)

Xiaoling Guo et al.

JOURNAL OF NEURORESTORATOLOGY (2020)

Article Developmental Biology

Ferroptosis and Brain Injury

Leslie Magtanong et al.

DEVELOPMENTAL NEUROSCIENCE (2019)

Review Pharmacology & Pharmacy

Pathophysiological Mechanisms and Potential Therapeutic Targets in Intracerebral Hemorrhage

Zhiwei Shao et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Biochemistry & Molecular Biology

Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos

Nirmal Robinson et al.

REDOX BIOLOGY (2019)

Article Oncology

Iduna protects HT22 cells by inhibiting parthanatos: The role of the p53-MDM2 pathway

Haoxiang Xu et al.

EXPERIMENTAL CELL RESEARCH (2019)

Article Biochemistry & Molecular Biology

Role of Mitochondria in Ferroptosis

Minghui Gao et al.

MOLECULAR CELL (2019)

Article Medicine, Research & Experimental

Potential role of poly (ADP-ribose) polymerase in delayed cerebral vasospasm following subarachnoid hemorrhage in rats

Yameng Fan et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)

Review Biochemistry & Molecular Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2018)

Review Neurosciences

Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options

Emine Sekerdag et al.

CURRENT NEUROPHARMACOLOGY (2018)

Review Biochemistry & Molecular Biology

An overview of apoptosis assays detecting DNA fragmentation

Pavlina Majtnerova et al.

MOLECULAR BIOLOGY REPORTS (2018)

Review Neurosciences

Injury mechanisms in acute intracerebral hemorrhage

D. Andrew Wilkinson et al.

NEUROPHARMACOLOGY (2018)

Article Neurosciences

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

Haiying Li et al.

PROGRESS IN NEUROBIOLOGY (2018)

Review Neurosciences

Programmed Cell Death after Intracerebral Hemorrhage

Tobias Bobinger et al.

CURRENT NEUROPHARMACOLOGY (2018)

Article Neurosciences

Regulated Necrosis Orchestrates Microglial Cell Death in Manganese-Induced Toxicity

Soledad Porte Alcon et al.

NEUROSCIENCE (2018)

Article Biotechnology & Applied Microbiology

AC-YVAD-CMK Inhibits Pyroptosis and Improves Functional Outcome after Intracerebral Hemorrhage

Xiao Lin et al.

BIOMED RESEARCH INTERNATIONAL (2018)

Article Clinical Neurology

RIP1 and RIP3 mediate hemin-induced cell death in HT22 hippocampal neuronal cells

Xingfen Su et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2018)

Article Endocrinology & Metabolism

Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis

Jian Zhang et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)

Article Clinical Neurology

Minocycline in Acute Cerebral Hemorrhage An Early Phase Randomized Trial

Abdelrahman Y. Fouda et al.

STROKE (2017)

Review Biochemistry & Molecular Biology

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell et al.

Article Medicine, Research & Experimental

Inhibition of neuronal ferroptosis protects hemorrhagic brain

Qian Li et al.

JCI INSIGHT (2017)

Article Biochemistry & Molecular Biology

USP11, Deubiquitinating Enzyme, Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage

Zhiwei Xu et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2016)

Review Neurosciences

Functional outcome after intracerebral haemorrhage - a review of the potential role of antiapoptotic agents

Abubakar Tijjani Salihu et al.

REVIEWS IN THE NEUROSCIENCES (2016)

Review Biochemistry & Molecular Biology

Ferroptosis: process and function

Y. Xie et al.

CELL DEATH AND DIFFERENTIATION (2016)

Review Biochemistry & Molecular Biology

Mechanisms of ferroptosis

Jennifer Yinuo Cao et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Biochemistry & Molecular Biology

Autophagy regulates intracerebral hemorrhage induced neural damage via apoptosis and NF-κB pathway

Xi Shen et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

Review Cell Biology

Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy

Xiaochun Duan et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Cell Biology

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

Tarique Hussain et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Review Cell Biology

TNF and ROS Crosstal in Inflammation

Heiko Blaser et al.

TRENDS IN CELL BIOLOGY (2016)

Review Critical Care Medicine

The critical care management of spontaneous intracranial hemorrhage: a contemporary review

Airton Leonardo de Oliveira Manoel et al.

CRITICAL CARE (2016)

Review Biochemistry & Molecular Biology

Reactive Oxygen Species in Inflammation and Tissue Injury

Manish Mittal et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Article Immunology

The role of aquaporin 4 in apoptosis after intracerebral hemorrhage

Heling Chu et al.

JOURNAL OF NEUROINFLAMMATION (2014)

Article Cell Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

NATURE CELL BIOLOGY (2014)

Article Critical Care Medicine

Hydrogen Inhalation Ameliorated Mast Cell-Mediated Brain Injury After Intracerebral Hemorrhage in Mice

Anatol Manaenko et al.

CRITICAL CARE MEDICINE (2013)

Article Clinical Neurology

Nrf2 to Pre-condition the Brain Against Injury Caused by Products of Hemolysis After ICH

Xiurong Zhao et al.

TRANSLATIONAL STROKE RESEARCH (2013)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Article Neurosciences

Thrombin-induced autophagy: A potential role in intracerebral hemorrhage

Shukun Hu et al.

BRAIN RESEARCH (2011)

Review Biochemistry & Molecular Biology

AIF-mediated Caspase-independent Necroptosis: A New Chance for Targeted Therapeutics

Laure Delavallee et al.

IUBMB LIFE (2011)

Review Biochemistry & Molecular Biology

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

G. Kroemer et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Biochemistry & Molecular Biology

No death without life: vital functions of apoptotic effectors

L. Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Biochemistry & Molecular Biology

Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes

Melissa D. Laird et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Neurosciences

Oxidative DNA injury after experimental intracerebral hemorrhage

T Nakamura et al.

BRAIN RESEARCH (2005)

Article Multidisciplinary Sciences

Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats

CMP Rodrigues et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Endocrinology & Metabolism

Evidence for apoptosis after intracerebral hemorrhage in rat striatum

K Matsushita et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2000)