The combined effect of lifestyle intervention and antioxidant therapy on sperm DNA fragmentation and seminal oxidative stress in IVF patients: a pilot study

Review Cell Biology

Effects of mobile phone radiofrequency radiation on sperm quality

Romualdo Sciorio et al.

Summary: Mobile phone radiation may have adverse effects on the male reproductive system, including a decline in sperm quality. Environmental and lifestyle factors also contribute to male infertility.

ZYGOTE (2022)

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Article Urology & Nephrology

Oxidative origin of sperm DNA fragmentation in the adult varicocele

Jessica Timoteo Jeremias et al.

Summary: This study found that patients with varicocele have significantly increased levels of sperm DNA fragmentation, particularly in oxidative stress-induced sperm DNA damage.

INTERNATIONAL BRAZ J UROL (2021)

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Article Urology & Nephrology

The association of seminal oxidation reduction potential with sperm parameters in patients with unexplained and male factor infertility

Ozge Senem Yucel Cicek et al.

Summary: Understanding the effects of high oxidation reduction potential (ORP) levels on sperm parameters revealed a significant decrease in total sperm count, sperm concentration, and total motile sperm count in samples with sORP values >1.36mV/10(6)sperm/mL. This study suggests that seminal oxidative stress, as indicated by sORP cutoff, is associated with oligozoospermia, reduced progressive motility, and low total motile sperm count in semen analysis.

INTERNATIONAL BRAZ J UROL (2021)

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Editorial Material Urology & Nephrology

Best urological practices on testing and management of infertile men with abnormal sperm DNA fragmentation levels: the SFRAG guidelines

Sandro C. Esteves

INTERNATIONAL BRAZ J UROL (2021)

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Review Obstetrics & Gynecology

Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

Filipe Tenorio Lira Neto et al.

Summary: This study found that varicocelectomy can reduce sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele. Men with elevated preoperative SDF levels showed a more significant treatment effect after the surgery.

FERTILITY AND STERILITY (2021)

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Review Andrology

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

Sandro C. Esteves et al.

Summary: This article summarizes the impact of sperm DNA fragmentation in various clinical infertility scenarios and advances in sperm DNA fragmentation tests. Based on collected evidence, 41 recommendations were formulated, covering technical aspects, clinical thresholds, interpretation of results, indications for testing, and clinical management. The bulk of evidence supporting these recommendations has increased in recent years, although it is still of moderate to low quality.

ANDROLOGIA (2021)

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Article Obstetrics & Gynecology