期刊
JOURNAL OF CHEMICAL RESEARCH
卷 46, 期 1, 页码 -出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/17475198211072498
关键词
antimicrobial; antioxidant; Celastraceae; chlorophyll; Gymnosporia senegalensis; megastigmane
资金
- Matsumae International Foundation (MIF)
- University of Maroua, Cameroon
The investigation of the non-polar and polar fractions of ethyl acetate extract from Gymnosporia senegalensis leaves resulted in the isolation of nine compounds, including a new megastigmane derivative and known derivatives of galloyl, chlorophyll, and fatty acid. The compounds were tested for their antibacterial, antifungal, and antioxidant activities, showing various levels of effectiveness.
Investigation of the non-polar (rich in chlorophyll) and polar fractions of the ethyl acetate extract of Gymnosporia senegalensis (Lam.) Loes. leaves led to the isolation of nine compounds, including one new megastigmane derivative, (3R*,5S*,6R*,7E,9 xi)-7-megastigmene-3,6,9-triol-3-O-beta-D-(6 '-O-galloyl)glucopyranoside (1), four known galloylated derivatives (2, 3, 8, 9), three known chlorophyll derivatives (4-6), and one known fatty acid (7). The structures of the isolates were determined by means of spectroscopic and spectrometric data, as well as by comparison with literature values. The extracts and isolated compounds were tested for their antibacterial, antifungal, and antioxidant activities. The isolates showed weak to high antimicrobial activities with phaeophytin A (4) being the most active one whereas phaeophorbide-a (5) and Chlorine e(6) trimethyl ester (6) exhibited the highest antioxidant activities.
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