相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Opposing effects of T cell receptor signal strength on CD4 T cells responding to acute versus chronic viral infection
Marco Kunzli et al.
ELIFE (2021)
Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection
Heidi J. Elsaesser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection
Nike Julia Kraeutler et al.
CELL REPORTS (2020)
Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
Benedict Fallet et al.
CELL REPORTS (2020)
Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection
Ioana Sandu et al.
CELL REPORTS (2020)
Sphingosine kinase 2 restricts T cell immunopathology but permits viral persistence
Caleb J. Studstill et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
Brian C. Miller et al.
NATURE IMMUNOLOGY (2019)
IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection
Zhe Huang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
Francesca Alfei et al.
NATURE (2019)
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
Omar Khan et al.
NATURE (2019)
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
Chen Yao et al.
NATURE IMMUNOLOGY (2019)
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
Martin W. LaFleur et al.
NATURE IMMUNOLOGY (2019)
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
Zeyu Chen et al.
IMMUNITY (2019)
Emerging Connections of S1P-Metabolizing Enzymes with Host Defense and Immunity During Virus Infections
Jennifer J. Wolf et al.
VIRUSES-BASEL (2019)
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
Alexander Lercher et al.
IMMUNITY (2019)
Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
William H. Hudson et al.
IMMUNITY (2019)
CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
Ryan Zander et al.
IMMUNITY (2019)
Regulation of autoimmune and anti-tumour T-cell responses by PTPN22
Rebecca J. Brownlie et al.
IMMUNOLOGY (2018)
Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection
James A. Harker et al.
JOURNAL OF VIROLOGY (2018)
Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1
Daniel T. Utzschneider et al.
CELL REPORTS (2018)
The adaptor molecule CD2AP in CD4 T cells modulates differentiation of follicular helper T cells during chronic LCMV infection
Saravanan Raju et al.
PLOS PATHOGENS (2018)
Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice
Chuan Xia et al.
ANTIVIRAL RESEARCH (2018)
Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection
Gang Xin et al.
NATURE COMMUNICATIONS (2018)
The diverse functions of the PD1 inhibitory pathway
Arlene H. Sharpe et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence Of Chronic Lymphocytic Choriomeningitis Virus Infection
Tatiana Jofra et al.
FRONTIERS IN IMMUNOLOGY (2017)
CD30 Is Dispensable for T-Cell Responses to Influenza Virus and Lymphocytic Choriomeningitis Virus Clone 13 but Contributes to Age-Associated T-Cell Expansion in Mice
Angela C. Zhou et al.
FRONTIERS IN IMMUNOLOGY (2017)
Sustained T follicular helper cell response is essential for control of chronic viral infection
Ute Greczmiel et al.
SCIENCE IMMUNOLOGY (2017)
New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function
Shin-Huei Fu et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion
Roberto Tinoco et al.
IMMUNITY (2016)
The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis
Carmen Gerlach et al.
IMMUNITY (2016)
T Cell Factor 1-Expressing Memory-like CD8+ T Cells Sustain the Immune Response to Chronic Viral Infections
Daniel T. Utzschneider et al.
IMMUNITY (2016)
Dynamic Changes in Chromatin Accessibility Occur in CD8+ T Cells Responding to Viral Infection
James P. Scott-Browne et al.
IMMUNITY (2016)
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8+ T Cell Exhaustion
Bertram Bengsch et al.
IMMUNITY (2016)
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
Ana C. Anderson et al.
IMMUNITY (2016)
High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival
Daniel T. Utzschneider et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
LAG-3 Confers a Competitive Disadvantage upon Antiviral CD8+ T Cell Responses
Kevin D. Cook et al.
JOURNAL OF IMMUNOLOGY (2016)
Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
Ran He et al.
NATURE (2016)
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
Se Jin Im et al.
NATURE (2016)
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
Yew Ann Leong et al.
NATURE IMMUNOLOGY (2016)
PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection
Christian J. Maine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The epigenetic landscape of T cell exhaustion
Debattama R. Sen et al.
SCIENCE (2016)
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Kristen E. Pauken et al.
SCIENCE (2016)
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness
Tuoqi Wu et al.
SCIENCE IMMUNOLOGY (2016)
Interferon-driven deletion of antiviral B cells at the onset of chronic infection
Benedict Fallet et al.
SCIENCE IMMUNOLOGY (2016)
The Transcription Factor NFAT Promotes Exhaustion of Activated CD8+ T Cells
Gustavo J. Martinez et al.
IMMUNITY (2015)
TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection
Tuoqi Wu et al.
CELL REPORTS (2015)
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
Yu-Hwa Huang et al.
NATURE (2015)
The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8+ T Cell Effector Function
Robert J. Johnston et al.
CANCER CELL (2014)
LSECtin Expressed on Melanoma Cells Promotes Tumor Progression by Inhibiting Antitumor T-cell Responses
Feng Xu et al.
CANCER RESEARCH (2014)
Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1
Josh Crouse et al.
IMMUNITY (2014)
Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection
Alison Crawford et al.
IMMUNITY (2014)
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1
Ian A. Parish et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
PTPN2 attenuates T-cell lymphopenia-induced proliferation
Florian Wiede et al.
NATURE COMMUNICATIONS (2014)
Correction: Impaired Antibody Response Causes Persistence of Prototypic T Cell–Contained Virus
Andreas Bergthaler et al.
PLOS BIOLOGY (2014)
Cell-Intrinsic IL-27 and gp130 Cytokine Receptor Signaling Regulates Virus-Specific CD4+ T Cell Responses and Viral Control during Chronic Infection
James A. Harker et al.
IMMUNITY (2013)
Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes
Michael A. Paley et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2013)
Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection
Elizabeth B. Wilson et al.
SCIENCE (2013)
Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling
John R. Teijaro et al.
SCIENCE (2013)
Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
Travis A. Doering et al.
IMMUNITY (2012)
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion
Manu Rangachari et al.
NATURE MEDICINE (2012)
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering
Katharina F. Stengel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection
Michael A. Paley et al.
SCIENCE (2012)
TGF-β Blockade Does Not Improve Control of an Established Persistent Viral Infection
Tobias Boettler et al.
VIRAL IMMUNOLOGY (2012)
Evolving role of 2B4/CD244 in T and NK cell responses during virus infection
Stephen N. Waggoner et al.
FRONTIERS IN IMMUNOLOGY (2012)
Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load
Erin E. West et al.
IMMUNITY (2011)
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
Laura M. Fahey et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions
Nicole Joller et al.
JOURNAL OF IMMUNOLOGY (2011)
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
Charlly Kao et al.
NATURE IMMUNOLOGY (2011)
IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation
Danelle Eto et al.
PLOS ONE (2011)
Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence
Brian M. Sullivan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection
Rachael D. Aubert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection
James A. Harker et al.
SCIENCE (2011)
Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1
Xinyuan Zhou et al.
IMMUNITY (2010)
Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion
Shawn D. Blackburn et al.
JOURNAL OF VIROLOGY (2010)
Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
Andreas Bergthaler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
Hyun-Tak Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cell-Intrinsic Transforming Growth Factor-β Signaling Mediates Virus-Specific CD8+ T Cell Deletion and Viral Persistence In Vivo
Roberto Tinoco et al.
IMMUNITY (2009)
The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation
Guifang Cai et al.
IMMUNOLOGICAL REVIEWS (2009)
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells
Oliver Dienz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
Shawn D. Blackburn et al.
NATURE IMMUNOLOGY (2009)
High antigen levels are the cause of T cell exhaustion during chronic viral infection
Scott N. Mueller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
Nitai C. Hait et al.
SCIENCE (2009)
A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
John S. Yi et al.
SCIENCE (2009)
IL-21 Is Required to Control Chronic Viral Infection
Heidi Elsaesser et al.
SCIENCE (2009)
IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection
Anja Froehlich et al.
SCIENCE (2009)
Interleukin-21: Basic biology and implications for cancer and autoimmunity
Rosanne Spolski et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
NFATc1 regulates PD-1 expression upon T cell activation
Kenneth J. Oestreich et al.
JOURNAL OF IMMUNOLOGY (2008)
CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator
Guifang Cai et al.
NATURE IMMUNOLOGY (2008)
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells
Thomas Korn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection
David G. Brooks et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade
Shawn D. Blackburn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
E. John Wherry et al.
IMMUNITY (2007)
Interleukin-21:: A new modulator of immunity, infection, and cancer
Katja Brandt et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2007)
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection
Haina Shin et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Resolution of a chronic viral infection after interleukin-10 receptor blockade
Mette Ejrnaes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Restoring function in exhausted CD8 T cells during chronic viral infection
DL Barber et al.
NATURE (2006)
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
C Zhu et al.
NATURE IMMUNOLOGY (2005)
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer et al.
NATURE IMMUNOLOGY (2005)
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
GA Kolumam et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
2B4/CD48-mediated regulation of lymphocyte activation and function
E Assarsson et al.
JOURNAL OF IMMUNOLOGY (2005)
Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection
DG Brooks et al.
JOURNAL OF VIROLOGY (2005)
Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory
FMC Gaspal et al.
JOURNAL OF IMMUNOLOGY (2005)
2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells
ME McNerney et al.
MOLECULAR IMMUNOLOGY (2005)
Negative regulation of T cell homeostasisby lymphocyte activation gene-3 (CD223)
CJ Workman et al.
JOURNAL OF IMMUNOLOGY (2005)
Antigen-independent memory CD8 T cells do not develop during chronic viral infection
EJ Wherry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis
N Igarashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression
HC Probst et al.
JOURNAL OF IMMUNOLOGY (2003)
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
EJ Wherry et al.
JOURNAL OF VIROLOGY (2003)
Ablation of CD8 and CD4 T cell responses by high viral loads
MJ Fuller et al.
JOURNAL OF IMMUNOLOGY (2003)
LAG-3: a regulator of T-cell and DC responses and its use in therapeutic vaccination
F Triebel
TRENDS IN IMMUNOLOGY (2003)
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
L Monney et al.
NATURE (2002)
Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics
SC Smelt et al.
JOURNAL OF VIROLOGY (2001)
Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection
JN Blattman et al.
JOURNAL OF IMMUNOLOGY (2000)
Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells
N Sevilla et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
分享论文
