☆ 4.1 Article

The crystal structure of (Z)-2-(4-(4-bromophenyl)thiazol-2-yl)-4-(3-hydroxybut-2-enoyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one - methanol (1/1), C18H18N3O4S

ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES (2022)

A Therapeutic Journey of 5-Pyrazolones as a Versatile Scaffold: A Review

Ravinder Sharma et al.

Summary: Derivatives of 5-pyrazolone have shown diverse activities and some drugs based on this structure have been marketed. Different approaches for the synthesis of 5-pyrazolones have been cited. This review provides insights into the synthesis, biological profile, and structure-activity relationship studies of 5-pyrazolones.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2021)

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Review Chemistry, Medicinal