☆ 4.5 Review

Combinational application of metal-organic frameworks-based nanozyme and nucleic acid delivery in cancer therapy

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Chitosan-coated Zn-metal-organic framework nanocomposites for effective targeted delivery of LNA-antisense miR-224 to colon tumor: in vitro studies

Negin Mokri et al.

Summary: Nano-compartments are considered as an effective drug delivery system for cancer therapy. A novel zinc-based nanoscale metal-organic framework coated with folic acid functionalized chitosan was constructed for efficient delivery of LNA-antisense miR-224 to colon cancer cells. The nanocomplex showed promising therapeutic efficiency in inhibiting the growth of colon cancer cells and inducing cell apoptosis.

GENE THERAPY (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Cascade-responsive nanobomb with domino effect for anti-tumor synergistic therapies

Yang Liu et al.

Summary: In this study, a cascade-responsive ROS nanobomb was designed to selectively generate multiple powerful ROS storms at tumor sites without external stimulation, thus effectively activating anti-tumor immune response.

NATIONAL SCIENCE REVIEW (2022)

添加到收藏夹

Review Oncology

Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges

Zeenat Mirza et al.

Summary: Breast cancer is one of the deadliest cancers in females, and traditional treatment methods often fall short due to various limitations. Nanoparticles have the potential to revolutionize breast cancer gene therapy by improving circulation time, enhancing bioavailability, reducing immune system recognition, and accurately delivering gene regulators. Their targeted drug delivery mechanisms and advancements in therapeutic strategies show promise for future treatments of breast cancer.

SEMINARS IN CANCER BIOLOGY (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy

Xiangrong Song et al.

Summary: CRISPR/Cas systems are efficient and versatile gene editing tools with enormous potential for cancer treatment. While preclinical studies using CRISPR/Cas systems for cancer treatment are underway, efficient and safe in vivo delivery remains a critical challenge for their clinical applications.

ADVANCED DRUG DELIVERY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Co-delivery of anticancer drugs and cell penetrating peptides for improved cancer therapy

Xiao Fu et al.

Summary: The study demonstrated the one-pot synthesis of poly(ethylene glycol) mediated ZIF-8 NPs for the co-delivery of an anticancer drug and a cell-penetrating peptide to improve therapeutic efficacy. These pH-responsive NPs showed stability at neutral pH and released the encapsulated drugs at acidic pH, enhancing their cytotoxicity. This strategy provides a new perspective for the design of drug delivery systems and offers more opportunities for biomedical applications.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Tumor Diagnosis and Therapy Mediated by Metal Phosphorus-Based Nanomaterials

Yang Liu et al.

Summary: Metal phosphorus-based nanomaterials, including metal phosphate nanomaterials, metal phosphide nanomaterials, and metal-black phosphorus nanocomposites, have been widely used in biomedicine due to their excellent physical and chemical properties. They have shown great potential in tumor diagnosis and therapy, with metal phosphate nanomaterials demonstrating good biodegradability and metal phosphide nanomaterials exhibiting excellent optical, magnetic, and catalytic properties for multifunctional diagnostic and therapeutic applications. The latest developments in Metal-P NMs, focusing on preparation methods and biological applications, highlight their importance in advancing research and knowledge in this field.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Tumor-Associated Macrophage and Tumor-Cell Dually Transfecting Polyplexes for Efficient Interleukin-12 Cancer Gene Therapy

Nasha Qiu et al.

Summary: A novel IL12 gene-delivery vector was designed to efficiently transfect both cancer cells and TAMs, turning them into a factory for IL12 production, which effectively activates anticancer immune responses and remodels the tumor microenvironment. The intravenously administered vector slows tumor growth and doubles survival in three animal models with minimal systemic toxicities.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Engineering, Environmental

Exosome derived from mesenchymal stem cells mediates hypoxia-specific BMP2 gene delivery and enhances bone regeneration

Zhuo Liang et al.

Summary: A novel gene delivery vector was developed using a layer-by-layer self-assembly method with PEI and Exos derived from MSCs, which exhibited high transfection efficiency and low cytotoxicity to MSCs. Additionally, a hypoxia-specific expression plasmid combining hypoxia promoter RTP801 and miR877 sponge significantly increased BMP2 expression in hypoxic conditions and promoted neoangiogenesis, providing a potential method to enhance bone repair in tissue engineering.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Chemistry, Physical

Combined chemo-photothermal treatment of three-dimensional head and neck squamous cell carcinomas by gold nano-architectures

Ana Katrina Mapanao et al.

Summary: This study presents a synergistic chemophotothermal treatment method using ultrasmall-in-nano gold architectures for head and neck squamous cell carcinomas, showing more pronounced antitumor action on HPV-positive HNSCCs. The findings suggest the potential clinical relevance of noble metal-based synergistic treatments for tumor management.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

添加到收藏夹

Review Urology & Nephrology

Defining cisplatin eligibility in patients with muscle-invasive bladder cancer

Di Maria Jiang et al.

Summary: The study proposes a new treatment framework to reduce excessive exclusion of patients with muscle-invasive bladder cancer from cisplatin-based neoadjuvant chemotherapy. The algorithm emphasizes a multidisciplinary and patient-centered approach to assess cisplatin eligibility, aiming to improve treatment outcomes and standardize clinical trial designs for patients with MIBC.

NATURE REVIEWS UROLOGY (2021)

添加到收藏夹

Article Chemistry, Physical

An electrochemical biosensor based on hemin/G-quadruplex DNAzyme and PdRu/Pt heterostructures as signal amplifier for circulating tumor cells detection

Xi Zhou et al.

Summary: In this study, hierarchical structures of PtNPs decorated with hyperbranched PdRu nanospines were synthesized for efficient detection of CTCs. Multiplexed signal amplification significantly improved the analytical performance of the biosensor, with a detection limit for CTCs of 2 cells mL(-1).

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Dual Roles of Metal-Organic Frameworks as Nanocarriers for miRNA Delivery and Adjuvants for Chemodynamic Therapy

Huaixin Zhao et al.

Summary: This study reveals the dual roles of metal-organic framework nanoparticles in miRNA delivery and chemodynamic therapy, demonstrating high efficacy in synergistic gene/chemodynamic therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanozymes: A clear definition with fuzzy edges

Hui Wei et al.

NANO TODAY (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Topical formulations containing aptamer-functionalized nanocapsules loaded with 5-fluorouracil - An innovative concept for the skin cancer therapy

Delia Mihaela Rata et al.

Summary: The new topical gel formulations containing AS1411 aptamer-functionalized polymeric nanocapsules loaded with an antitumoral drug showed promising potential for skin cancer treatment. Characterization tests including rheological, permeation, hemolysis, skin irritation, cytotoxicity and in vivo tests demonstrated the safety and effectiveness of the gel formulations. Nanoencapsulation of 5-Fluorouracil enhanced its permeability and cytotoxicity, making it an attractive option for skin cancer therapy.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo

Mingjing Cao et al.

Summary: Understanding the in vivo biotransformation of nanomaterials, such as molybdenum derived from MoS2, can shed light on their long-term effects on liver metabolism. Through a combination of in vivo experiments and molecular dynamics simulations, the study reveals that the biodistribution of molybdenum is mediated by protein coronas, mainly with apolipoprotein E, leading to increased enzyme activities in the liver. The findings suggest that nanomaterials consisting of essential trace elements may be converted into active biological molecules in organisms.

NATURE NANOTECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Analytical

Dual-quenching electrochemiluminescence resonance energy transfer system from IRMOF-3 coreaction accelerator enriched nitrogen-doped GQDs to ZnO@Au for sensitive detection of procalcitonin

Lihua Hu et al.

Summary: A novel ECL-RET pair was designed using IRMOF-3 enriched N-GQDs and ZnO@Au for the fabrication of a dual-quenching sandwich-type ECL immunosensor for ultrasensitive analysis of PCT. The system showed high sensitivity and a wide detection range, with a limit of detection of 12.58 fg mL(-1) in human serum samples, demonstrating its potential for effective detection of disease markers in clinical medicine.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

添加到收藏夹

Article Engineering, Biomedical

Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer

Ye Liang et al.

Summary: This study developed a CD44 targeted gene delivery system based on natural macromolecules for effective bladder cancer treatment, which could be more conducive to clinical application due to its simple preparation and high biological safety.

BIOACTIVE MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Target Reprogramming Lysosomes of CD8+T Cells by a Mineralized Metal-Organic Framework for Cancer Immunotherapy

Qin Zhao et al.

Summary: The study introduces a lysosome-targeting nanoparticle developed from a mineralized metal-organic framework coupled with a lysosome-targeting aptamer to enhance the antitumor effect of T cells. The MOF synthesized from Zn2+ and dimethylimidazole has good protein encapsulation and acid sensitivity, making it an ideal lysosomal delivery vector. The use of calcium carbonate to induce MOF mineralization improves stability and provides synergistic effects for encapsulating therapeutic proteins.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multifunctional Graphdiyne-Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer

Xuantong Zhou et al.

Summary: Radioresistance poses a significant challenge in clinical treatments, attributed to factors such as hypoxia in the tumor microenvironment, antioxidant systems in cancer cells, and upregulation of DNA repair proteins. A novel strategy involving GDY-CeO2 nanocomposites and miR181a shows promise in overcoming radioresistance and enhancing therapeutic efficacy in ESCC patients by mitigating hypoxia, promoting DNA damage, and facilitating personalized treatment.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Bimetallic Metal-Organic Framework Encapsulated with DNAzyme for Intracellular Drug Synthesis and Self-Sufficient Gene Therapy

Zhao Wang et al.

Summary: A novel treatment method has been designed to achieve co-triggered in situ cancer drug synthesis and gene therapy by using MOF encapsulated with DNAzyme, minimizing the damage to normal cells.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Chemistry, Physical

Recent Advances in Nucleic Acid Modulation for Functional Nanozyme

Xin Wang et al.

Summary: This article discusses the application of nanozymes in energy conversion technology and the influence of nucleic acids on modulation principles, classifying functional nanozymes into three categories and summarizing the effects of nucleic acids on modulation. Furthermore, the latest developments of nucleic acid-modulated nanozymes in energy conversion technology are explored, highlighting the advantages and limitations of functional nanozymes.

CATALYSTS (2021)

添加到收藏夹

Article Chemistry, Analytical

Heterojunction of Vertically Arrayed MoS2 Nanosheet/N-Doped Reduced Graphene Oxide Enabling a Nanozyme for Sensitive Biomolecule Monitoring

Longwei Wang et al.

Summary: The article introduces a novel nanozyme with good stability and superior catalytic kinetics, capable of sensitively detecting biomolecules such as glucose and glutathione. The development of this artificial nanozyme is expected to contribute to sensitive detection of other biomolecules in physiological conditions in the future.

ANALYTICAL CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Titanium Nitride Nanozyme for pH-Responsive and Irradiation-Enhanced Cascade-Catalytic Tumor Therapy

Jiaming Liu et al.

Summary: The study found that nitrogen doping significantly enhanced the peroxidase activity of titanium-based nanozymes, and further improved the catalytic activity of nanozymes under near-infrared laser irradiation. By using TLGp, combining pH-responsive GOx-mediated H2O2 self-supply, nitrogen doping, and irradiation-enhanced enzymatic activity of titanium nitride nanoparticles, along with mild photothermal therapy, effective tumor inhibition with minimal side effects in vivo was achieved.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Engineering, Biomedical

Tailoring metal-organic frameworks-based nanozymes for bacterial theranostics

Arbab Ali et al.

Summary: MOFs are a new type of material with unique properties that bridge the gap between natural enzymes and nanozymes, offering potential for effective bacterial theranostics. Their design and fabrication, applications in bacterial theranostics, and future development opportunities were discussed in this review.

BIOMATERIALS (2021)

添加到收藏夹

Article Engineering, Environmental

Biomineralized DNA nanospheres by metal organic framework for enhanced chemodynamic therapy

Peipei Wang et al.

Summary: In this study, metal organic framework (MOF)-biomineralized DNA nanospheres were developed as chemodynamic therapy (CDT) agents with tumor-activable cascade reactions for boosting intracellular H2O2 concentration, achieving remarkable antitumor outcome. The CDT agent utilizes tumor acid-induced dissociation to release Fe2+/Fe3+ for Fenton reaction and GOx for catalyzing glucose into H2O2, synergistically elevating ROS level in tumor cells to induce ferroptosis. This strategy provides a promising approach for developing CDT agents with improved therapeutic efficacy.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Engineering, Environmental

Metal-organic frameworks for simultaneous gene and small molecule delivery in vitro and in vivo

A. Ringaci et al.

Summary: This study presents a novel nanoscale modified MOFs that allow co-delivery of a transgene and a drug-like molecule, opening up new opportunities for gene delivery while retaining the advantages of small molecule transport. Experimental results demonstrate the performance of these multimodal nanoparticles in vitro for different cell lines and in vivo upon intravenous injection in mice, showing potential applications in lung disease treatment.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Engineering, Environmental

Drug resistance reversal by interventing cancer bioenergetics with spherical helical polypeptide-potented gene silencing

Jian Shu et al.

Summary: This study presents a promising strategy to reverse drug resistance in cancer by intervening in cancer bioenergetics using RNA interference. The development of a densely packed, guanidine-rich spherical helical polypeptide for encapsulating chemotherapeutic drugs and siRNA shows potential for enhancing drug delivery and inhibiting drug efflux. The down-regulation of PKM2 through RNA interference effectively suppresses glycolysis metabolism, depletes energy supply for drug transporters, and induces apoptosis, thereby improving the efficacy of chemotherapy against drug-resistant tumors.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Overcoming thickened pathological skin in psoriasis via iontophoresis combined with tight junction-opening peptide AT1002 for intradermal delivery of NF-xB decoy oligodeoxynucleotide

Tatsuya Fukuta et al.

Summary: Combining tight junction-opening peptide AT1002 with iontophoresis (IP) can overcome the thickened pathological skin in psoriasis, facilitate macromolecule delivery, and enable intradermal delivery of NF-xB decoy oligodeoxynucleotide for psoriasis treatment.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Combining gene therapy with other therapeutic strategies and imaging agents for cancer theranostics

Alexandro Azevedo et al.

Summary: Cancer is a prevalent and deadly disease in need of new preventive and treatment strategies. The fields of cancer nanomedicine and nanotheranostics offer opportunities for personalized and targeted therapy through combining imaging and therapeutic agents. Gene therapy is a promising approach that requires efficient delivery systems, and recent developments in theranostic nanosystems are exploring the integration of gene therapy and imaging for cancer treatment.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

添加到收藏夹

Article Chemistry, Physical

Selective hydroboration of alkynes via multisite synergistic catalysis by PCN-222(Cu)

L. J. Zhang et al.

Summary: In this study, a highly efficient synthetic method for (E)-b-vinylboronates using PCN-222 as a catalyst was developed, achieving high TOF value and specific selectivity in the hydroboration reaction. The synergistic effect of central Cu(II) ions, N atoms of porphyrin rings, and terminal -OH groups on Zr-nodes played a key role in the process, as revealed by density functional theory (DFT) study.

JOURNAL OF CATALYSIS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

The reversal of chemotherapy-induced multidrug resistance by nanomedicine for cancer therapy

Shangui Liu et al.

Summary: Multidrug resistance is a persistent problem in cancer chemotherapy, but targeting the tumor microenvironment with multifunctional nanoparticles shows promise in overcoming this resistance.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

The Underlying Function and Structural Organization of the Intracellular Protein Corona on Graphdiyne Oxide Nanosheet for Local Immunomodulation

Mengyu Guo et al.

Summary: The study shows that carbon-based nanomaterial GDYO nanosheets interact with STAT3 protein, inducing the reeducation of immunosuppressive macrophages and triggering immune responses in the tumor microenvironment, potentially used for cancer immunotherapy.

NANO LETTERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent advances in enhanced chemodynamic therapy strategies

Qiwei Tian et al.

Summary: Chemodynamic therapy (CDT) is a novel therapeutic modality that aims to destroy cancer cells using Fenton reactions without external energy input. Various strategies have been explored to enhance the efficiency of CDT, including increasing the production, accelerating generation, and enhancing efficacy of hydroxyl radicals.

NANO TODAY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo

Safa Bazaz et al.

Summary: Splice-switching therapy with SSOs has shown promise for treating mis-splice disorders, but limited by poor bioavailability. Cell-penetrating peptides have gained attention for improving delivery of oligonucleotide compounds. By introducing hydrophobic modifications using hydrocarbon-modified amino acids, CPPs can effectively formulate SSOs into NPs for improved delivery efficacy in vitro and in vivo.

BIOMEDICINES (2021)

添加到收藏夹

Article Chemistry, Physical

Core-Shell Structured NH2-UiO-66@TiO2 Photocatalyst for the Degradation of Toluene under Visible Light Irradiation

Yi Zhou et al.

Summary: The study synthesized a core-shell structured MOF@TiO2 as an efficient photocatalyst for toluene degradation, exhibiting a higher degradation rate compared to pristine NH2-UiO-66. The NH2-UiO-66@TiO2 catalyst showed stable performance in repeated reuse experiments and a reactivation after washing with ethanol, with a photocatalytic mechanism involving efficient transfer of photogenerated holes and electrons to produce hydroxyl radicals and oxygen radicals for toluene oxidation. The construction of NH2-UiO-66@TiO2 is considered as an effective approach for the photocatalytic degradation of indoor air pollutants, providing new insights into core-shell structured MOF@photocatalysts design.

ACTA PHYSICO-CHIMICA SINICA (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

State of the Art and Prospects in Metal-Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis

Qi Wang et al.

CHEMICAL REVIEWS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Nanoscale Metal-Organic Framework to Mediate Photodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Enhance Antigen Presentation and Cancer Immunotherapy

Kaiyuan Ni et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Biophysics

A novel signal-off photoelectrochemical biosensor for M.SssI MTase activity assay based on GQDs@ZIF-8 polyhedra as signal quencher

Leixia Meng et al.

BIOSENSORS & BIOELECTRONICS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Co-Ferrocene MOF/Glucose Oxidase as Cascade Nanozyme for Effective Tumor Therapy

Chao Fang et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Optimizing Energy Transfer in Nanostructures Enables In Vivo Cancer Lesion Tracking via Near-Infrared Excited Hypoxia Imaging

Yantao Li et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Review Oncology

A review of cancer immunotherapy toxicity

Lucy Boyce Kennedy et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

添加到收藏夹

Article Cell Biology

Inhibition of miR-155 in MCF-7 breast cancer cell line by gold nanoparticles functionalized with antagomir and AS1411 aptamer

Arefeh Kardani et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes

Gyeungyun Kim et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Functional black phosphorus nanosheets for cancer therapy

Li Qin et al.

JOURNAL OF CONTROLLED RELEASE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks

Mram Z. Alyami et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bioinspired Construction of a Nanozyme-Based H2O2 Homeostasis Disruptor for Intensive Chemodynamic Therapy

Yanjuan Sang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Physical

Metal-organic frameworks nanoswitch: Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference

Gan Lin et al.

NANO RESEARCH (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Multifunctional siRNA-Laden Hybrid Nanoplatform for Noninvasive PA/IR Dual-Modal Imaging-Guided Enhanced Photogenetherapy

Jie Feng et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Designing Stimuli-Responsive Upconversion Nanoparticles that Exploit the Tumor Microenvironment

Muhammad Ovais et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enzyme-Triggered Disassembly of Perylene Monoimide-based Nanoclusters for Activatable and Deep Photodynamic Therapy

Yang Cai et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Oncology

Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

David S. Hong et al.

BRITISH JOURNAL OF CANCER (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Electrically Conductive Metal-Organic Frameworks

Lilia S. Xie et al.

CHEMICAL REVIEWS (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Two-Dimensional Nanosheet-Based Photonic Nanomedicine for Combined Gene and Photothermal Therapy

Na Yoon Kim et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

A triple-combination nanotechnology platform based on multifunctional RNA hydrogel for lung cancer therapy

Junwei Li et al.

SCIENCE CHINA-CHEMISTRY (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Metal-Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications

Yujia Sun et al.

NANO-MICRO LETTERS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles

Jia Zhuang et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Chemistry, Physical

Modulation of tumor microenvironment by metal-organic-framework-derived nanoenzyme for enhancing nucleus-targeted photodynamic therapy

Zeng Xuemei et al.

NANO RESEARCH (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Review of the Biomolecular Modification of the Metal-Organ-Framework

Qiqi Xing et al.

FRONTIERS IN CHEMISTRY (2020)

添加到收藏夹

Article Engineering, Biomedical

Au2Pt-PEG-Ce6 nanoformulation with dual nanozyme activities for synergistic chemodynamic therapy/phototherapy

Man Wang et al.

BIOMATERIALS (2020)

添加到收藏夹

Article Engineering, Biomedical

MOF-encapsulated nanozyme enhanced siRNA combo: Control neural stem cell differentiation and ameliorate cognitive impairments in Alzheimer's disease model

Dongqin Yu et al.

BIOMATERIALS (2020)

添加到收藏夹

Article Chemistry, Applied

Carbonized chitosan encapsulated hierarchical porous zeolitic imidazolate frameworks nanoparticles for gene delivery

Hani Nasser Abdelhamid et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2020)

添加到收藏夹

Article Chemistry, Applied

Gene delivery using cell penetrating peptides-zeolitic imidazolate frameworks

Hani Nasser Abdelhamid et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2020)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Advances in oligonucleotide drug delivery

Thomas C. Roberts et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

添加到收藏夹

Article Materials Science, Multidisciplinary

Bispecific T-cell engager (BiTE) immunotherapy of ovarian cancer based on MIL-88A MOF/MC gene delivery system

Jing Zhao et al.

APPLIED MATERIALS TODAY (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Core-Shell Nanosystems for Self-Activated Drug-Gene Combinations against Triple-Negative Breast Cancer

Peng Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Metal-organic frameworks-based nanozymes for combined cancer therapy

Shuai-shuai Ding et al.

NANO TODAY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Few-Layer Bismuthene for Checkpoint Knockdown Enhanced Cancer Immunotherapy with Rapid Clearance and Sequentially Triggered One-for-All Strategy

Mengyu Guo et al.

ACS NANO (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Defect-Rich Adhesive Molybdenum Disulfide/rGO Vertical Heterostructures with Enhanced Nanozyme Activity for Smart Bacterial Killing Application

Longwei Wang et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Article Chemistry, Physical

Fabrication of Z-Scheme Heterojunction of SiC/Pt/Cds Nanorod for Efficient Photocatalytic H2 Evolution

Dan Cao et al.

ACTA PHYSICO-CHIMICA SINICA (2020)

添加到收藏夹

Article Chemistry, Physical

Rod-Shaped Metal Organic Framework Structured PCN-222(Cu)/TiO2 Composites for Efficient Photocatalytic CO2 Reduction

Shuhua Duan et al.

ACTA PHYSICO-CHIMICA SINICA (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Graphene and other 2D materials: a multidisciplinary analysis to uncover the hidden potential as cancer theranostics

Laura Fusco et al.

THERANOSTICS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biocompatible iron(iii) carboxylate metal-organic frameworks as promising RNA nanocarriers

T. Hidalgo et al.

NANOSCALE (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent Advances in Subcellular Targeted Cancer Therapy Based on Functional Materials

Wei-Hai Chen et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

DNAzyme-Loaded Metal-Organic Frameworks (MOFs) for Self-Sufficient Gene Therapy

Huimin Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing

Xiaoti Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Biomimetic Coordination Nanoplatform for Controlled Encapsulation and Delivery of Drug-Gene Combinations

Bei Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Review Oncology

Targeting Ferroptosis to Iron Out Cancer

Behrouz Hassannia et al.

CANCER CELL (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong humoral and cellular immune responses

Xiaofang Zhong et al.

JOURNAL OF CONTROLLED RELEASE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Environmentally responsive dual-targeting nanotheranostics for overcoming cancer multidrug resistance

Caixia Yang et al.

SCIENCE BULLETIN (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Azoreductase-Responsive Metal-Organic Framework-Based Nanodrug for Enhanced Cancer Therapy via Breaking Hypoxia-induced Chemoresistance

Caixia Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Encapsulation of Plasmid DNA by Nanoscale Metal-Organic Frameworks for Efficient Gene Transportation and Expression

Yantao Li et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Biophysics

Recent progress in the design fabrication of metal-organic frameworks-based nanozymes and their applications to sensing and cancer therapy

Xianlong Zhang et al.

BIOSENSORS & BIOELECTRONICS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Local T regulatory cells depletion by an integrated nanodrug system for efficient chem-immunotherapy of tumor

Fan Gao et al.

SCIENCE CHINA-CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework-8 (ZIF-8)

Arpita Poddar et al.

SMALL (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy

Qishun Wang et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Engineering, Biomedical

Nanomaterial designing strategies related to cell lysosome and their biomedical applications: A review

Bhowmira Rathore et al.

BIOMATERIALS (2019)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Pharmacological modulation of nucleic acid sensors - therapeutic potential and persisting obstacles

Claire Vanpouille-Box et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

添加到收藏夹

Review Chemistry, Analytical

A review on metal-organic frameworks: Synthesis and applications

Mohadeseh Safaei et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Engineering Multifunctional DNA Hybrid Nanospheres through Coordination-Driven Self-Assembly

Mengyuan Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

One-Dimensional Fe2P Acts as a Fenton Agent in Response to NIR II Light and Ultrasound for Deep Tumor Synergetic Theranostics

Yang Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Zinc(II)-Dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/Gene Therapy

Chengchao Chu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Systems for stimuli-controlled release: Materials and applications

Marion Bruneau et al.

JOURNAL OF CONTROLLED RELEASE (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Value-added anticancer reactivity of sub-5 nm Ag-drug nanoparticles derived from organosilver(I) MOF

Chao-Yu Song et al.

SCIENCE CHINA-CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metal Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery

Wen Cai et al.

ADVANCED SCIENCE (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Tailoring Nanomaterials for Targeting Tumor-Associated Macrophages

Muhammad Ovais et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Article Materials Science, Biomaterials

Doxorubicin-loaded nanoscale metal-organic framework for tumor-targeting combined chemotherapy and chemodynamic therapy

Ting Xue et al.

BIOMATERIALS SCIENCE (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Graphdiyne Nanosheet-Based Drug Delivery Platform for Photothermal/Chemotherapy Combination Treatment of Cancer

Jun Jin et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Stable Metal-Organic Frameworks: Design, Synthesis, and Applications

Shuai Yuan et al.

ADVANCED MATERIALS (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment

Narsireddy Amreddy et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

添加到收藏夹

Review Multidisciplinary Sciences

The development of MOFs-based nanomaterials in heterogeneous organocatalysis

Xiaomei Liu et al.

SCIENCE BULLETIN (2018)

添加到收藏夹

Article Multidisciplinary Sciences

PEGylated mBPEI-rGO nanocomposites facilitate hepotocarcinoma treatment combining photothermal therapy and chemotherapy

Chunyi Tong et al.

SCIENCE BULLETIN (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

In Situ Synthesis of Ultrathin ZIF-8 Film-Coated MSNs for Codelivering Bcl 2 siRNA and Doxorubicin to Enhance Chemotherapeutic Efficacy in Drug-Resistant Cancer Cells

Qing-Shan Pan et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Metal-Organic Framework-Based Nanoplatform for Intracellular Environment-Responsive Endo/Lysosomal Escape and Enhanced Cancer Therapy

Kai Dong et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

Aptamer-based targeted therapy

Guizhi Zhu et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA

Jason B. Miller et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Organelle-Specific Triggered Release of Immunostimulatory Oligonucleotides from Intrinsically Coordinated DNA-Metal-Organic Frameworks with Soluble Exoskeleton

Zejun Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

添加到收藏夹

Article Materials Science, Biomaterials

A dendritic catiomer with an MOF motif for the construction of safe and efficient gene delivery systems

Shuqi Dong et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Poly(Vinylpyrollidone)- and Selenocysteine-Modified Bi2Se3 Nanoparticles Enhance Radiotherapy Efficacy in Tumors and Promote Radioprotection in Normal Tissues

Jiangfeng Du et al.

ADVANCED MATERIALS (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Se/Ru-Decorated Porous Metal-Organic Framework Nanoparticles for The Delivery of Pooled siRNAs to Reversing Multidrug Resistance in Taxol-Resistant Breast Cancer Cells

Qingchang Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in Vivo

Jing Liu et al.

ACS NANO (2016)

添加到收藏夹

Review Pharmacology & Pharmacy

Synergistic nanomedicine by combined gene and photothermal therapy

Jinhwan Kim et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

添加到收藏夹

Article Engineering, Biomedical

Controllable synthesis of dual-MOFs nanostructures for pH-responsive artemisinin delivery, magnetic resonance and optical dual-model imaging-guided chemo/photothermal combinational cancer therapy

Dongdong Wang et al.

BIOMATERIALS (2016)

添加到收藏夹

Article Nanoscience & Nanotechnology

Gadolinium(III)-Chelated Silica Nanospheres Integrating Chemotherapy and Photothermal Therapy for Cancer Treatment and Magnetic Resonance Imaging

Mingjing Cao et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bismuth Sulfide Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor

Jing Liu et al.

ACS NANO (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

Yantao Li et al.

ADVANCED MATERIALS (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Using Hollow Carbon Nanospheres as a Light-Induced Free Radical Generator To Overcome Chemotherapy Resistance

Liming Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

Taeyoung Koo et al.

MOLECULES AND CELLS (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Stimuli-Responsive Materials for Controlled Release of Theranostic Agents

Yucai Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2014)

添加到收藏夹

Review Immunology

Cellular and molecular mechanisms in cancer immune escape: a comprehensive review

Alka Bhatia et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near Infrared Laser-Induced Targeted Cancer Therapy Using Thermoresponsive Polymer Encapsulated Gold Nanorods

Zhenjiang Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nucleic Acid-Metal Organic Framework (MOF) Nanoparticle Conjugates

William Morris et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

添加到收藏夹

Review Genetics & Heredity

Non-viral vectors for gene-based therapy

Hao Yin et al.

NATURE REVIEWS GENETICS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near-Infrared Light-Mediated Nanoplatforms for Cancer Thermo-Chemotherapy and Optical Imaging

Zhenjiang Zhang et al.

ADVANCED MATERIALS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Pedro M. D. Moreno et al.

NUCLEIC ACIDS RESEARCH (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mesoporous Silica-Coated Gold Nanorods as a Light-Mediated Multifunctional Theranostic Platform for Cancer Treatment

Zhenjiang Zhang et al.

ADVANCED MATERIALS (2012)

添加到收藏夹

Article Nanoscience & Nanotechnology

Intrinsic peroxidase-like activity of ferromagnetic nanoparticles

Lizeng Gao et al.

NATURE NANOTECHNOLOGY (2007)

添加到收藏夹

Article Biochemistry & Molecular Biology

Growth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cells

S Napoli et al.

NUCLEIC ACIDS RESEARCH (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.