期刊
INTERNATIONAL HEART JOURNAL
卷 57, 期 2, 页码 134-139出版社
INT HEART JOURNAL ASSOC
DOI: 10.1536/ihj.15-346
关键词
Epicardial adipose tissue (EAT); Inflammation; MicroRNA (miRNA); Pentraxin 3 (PTX3)
资金
- Grants-in-Aid for Scientific Research [25293184] Funding Source: KAKEN
Atherosclerosis has been regarded as a form of chronic vascular inflammation. Numerous biomarkers associated with inflammation have been identified as novel targets to monitor atherosclerosis and cardiovascular risk. C-reactive protein (CRP) is one of the most actively studied and established inflammatory biomarkers for cardiovascular events. However, CRP response is triggered by many disorders unrelated to cardiovascular disease, which interferes with the clinical application. This review describes established and traditional inflammatory biomarkers including CRP as well as novel inflammatory biomarkers reflective of local atherosclerotic inflammation. In addition, we focus on the potential usefulness of inflammatory biomarkers in developing anti-atherosclerotic therapeutic approaches.
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