4.6 Article

Cost-Effectiveness of Systemic Treatments for Metastatic Castration- Sensitive Prostate Cancer: An Economic Evaluation Based on Network Meta-Analysis

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Comparison of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer A Systematic Review and Network Meta-analysis

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Summary: This study compared the effectiveness and safety of various systemic treatments for metastatic castration-sensitive prostate cancer through randomized clinical trials. Abiraterone acetate and apalutamide were found to potentially provide the largest overall survival benefits with relatively low risks of serious adverse events, while enzalutamide may improve radiographic progression-free survival to the greatest extent. Longer follow-up is needed to assess the overall survival benefits of enzalutamide.

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