Worldwide routine immunisation coverage regressed during the first year of the COVID-19 pandemic

Whilst COVID-19 vaccination strategies continue to receive considerable emphasis worldwide, the extent to which routine immunisation (RI) has been impacted during the first year of the pandemic remains unclear. Understanding the existence, extent, and variations in RI disruptions globally may help inform policy and resource prioritisation as the pandemic continues. We modelled historical, country-specific RI trends using publicly available vaccination coverage data for diphtheria, tetanus and pertussis-containing vaccine first-dose (DTP1) and third-dose (DTP3) from 2000 to 2019. We report a 2.9% (95 %(CI): [2.2%; 3.6%]) global decline in DTP3 coverage from an expected 89.2% to a reported 863%; and a 2.2% decline in DTP1 coverage (95 % a : [1.6%; 2.8%]). These declines translate to levels of coverage last observed in 2005, thus suggesting a potential 15-years setback in RI improvements. Further research is required to understand which factors - e.g., health seeking behaviours or non-pharmaceutical interventions - linked to the COVID-19 crisis impacted vaccination coverage. (C) 2022 The Authors. Published by Elsevier Ltd.

Automated summary

This study models the trends of vaccination coverage for diphtheria, tetanus, and pertussis-containing vaccines globally, and finds that routine immunization has been significantly disrupted during the first year of the COVID-19 pandemic, resulting in a decline in vaccination coverage. This setback in immunization progress poses a significant challenge.