4.7 Article

Antioxidant and anti-inflammatory polyphenols in ultrasound-assisted extracts from salvilla (Buddleja scordioides Kunth)

期刊

ULTRASONICS SONOCHEMISTRY
卷 83, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.ultsonch.2022.105917

关键词

Salvilla; Ultrasound-assisted extraction; Phenolic compounds; Antioxidant activity; Anti-inflammatory activity

资金

  1. Mexican Science and Technology Council (CONACYT-Mexico)
  2. Tecnologico Nacional de Mexico (SEP-TecNM) [100433.21-P]

向作者/读者索取更多资源

Salvilla is widely used in treatments against gastrointestinal disorders due to its antioxidant and anti-inflammatory potential. In this study, ultrasound-assisted extraction and ethanolic solutions were used to extract salvilla. The extracts contained a high amount of flavonoids and exhibited good antioxidant and anti-inflammatory activities. Treatment T6 (75% ethanol, 30% amplitude and 10 min extraction time) showed the highest flavonoid content, antioxidant activity, and anti-inflammatory potential.
Salvilla is a widely distributed plant used in treatments against gastrointestinal disorders due to its phenolic antioxidant and anti-inflammatory potential. Major yield and quality of bioactive polyphenols must be obtained with no degradation during suitable processes such as Ultrasound-Assisted Extraction (UAE), which allows an efficient extraction of metabolites at appropriate parameter conditions. Salvilla extractions were made using UAE and aqueous ethanolic solutions. Variables used in UAE were sonication time, wave amplitude and percentage of ethanol in solvent. Extracts were tested for total flavonoids, antioxidant activity (ABTS, FRAP and ORAC) and an identification and quantification of phenolic compounds was carried out by UPLC-PDA-ESI-MS/MS. Once elected the better extraction conditions, an anti-inflammatory test was performed for this treatment. As a result, total flavonoids content in extracts was 147 to 288 mu g catechin equivalents/mg of dry salvilla extract. All extracts have shown good antioxidant activity (86 to 280 mM Trolox eq/mg dry salvilla extract). Flavonoids contents by chromatography were higher than hydroxybenzoic and hydroxycinnamic acids specially the flavone, flavanol and flavanone groups. Treatment T6 (75% ethanol, 30% amplitude and 10 min extraction time) was the best extract in terms of significant flavonols, antioxidant activity, and higher anti-inflammatory potential.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据