Human autophagy measurement: an underappreciated barrier to translation

Preclinical research shows that autophagy is a modifiable process that holds promise for preventing human age-related disease. However, this knowledge has not been clinically translated. Here, we discuss recent developments in the ability to measure human autophagy, and why it is a critical step for translation.

Automated summary

Preclinical research suggests that autophagy could be modified to prevent age-related diseases in humans. Despite this, the translation of this knowledge into clinical practice has not yet been achieved. Measuring human autophagy capacity is crucial for this translation process.