Over the past two decades, thousands of genome-wide association studies have been conducted to identify marker-trait associations for complex traits in animals and plants, involving continuous improvement in methodology. Initially, a reference genome and SNPs were used, but more recently pan-genomes and markers structural variations (SVs)/k-mers are also being utilized.
For identification of marker-trait associations (MTAs) for complex traits in animals and plants, thousands of genome-wide association studies (GWAS) were conducted during the past two decades. This involved regular improvement in methodology. Initially, a reference genome and SNPs were used; more recently pan-genomes and the markers structural variations (SVs)/k-mers are also being used.
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