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Tao Wang et al.
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Qiong-Lin Wang et al.
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Bao T. Le et al.
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Yajun Wang et al.
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Shundong Cai et al.
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Zejun Wang et al.
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Zhenjian Zhuo et al.
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Issam Hmila et al.
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Yuuya Kasahara et al.
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Hanyang Yu et al.
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Vincent J. B. Ruigrok et al.
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Hanyang Yu et al.
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Troels B. Jensen et al.
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Prabodhika R. Mallikaratchy et al.
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Marina Zaitseva et al.
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Regina Stoltenburg et al.
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Chang Geng Peng et al.
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Carmelo Di Primo et al.
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F Li et al.
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M Berezovski et al.
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EWM Ng et al.
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V Kempeneers et al.
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