4.1 Article

Case of Anorchia in a Mixed-Breed Dog

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W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.tcam.2021.100554

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anorchia; cryptorchidism; testosterone; monorchidism; dog

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Anorchia is a rare disorder of sexual development, and in this case report, a 30-month old dog was diagnosed with anorchia using a multidisciplinary approach. The diagnostic process involved medical history collection, clinical examination, imaging studies, genetic testing, and hormone testing, ultimately confirming the diagnosis of testicular agenesis in the canine species.
Anorchia is a rare and often poorly understood disorder of sexual development. In the present case report, we used a multidisciplinary approach to diagnose a case of anorchia in a 30-month old dog. The diagnostic process began with gathering the dog medical history followed by a clinical visit with the patient, which included a general wellness examination as well as an examination of the genital system. As suggested in the relevant literature, the dog underwent an ultrasound and then computed tomography (CT) of the genital system, which confirmed the diagnosis of testicular agenesis. Genetic testing confirmed the male XY karyotype. Hormone testing also supported the diagnosis: testosterone and anti-Mu euro llerian hormone levels were below their reference ranges, and luteinizing hormone (LH) was above 1 ng/mL. Following the diagnostic procedures suggested in the relevant literature, the present study confirms anorchia in the dog and describes a case of testicular agenesis in the canine species. (c) 2021 Elsevier Inc. All rights reserved.

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