4.6 Article

In vitro cytotoxic effects of 5-Fluorouracil on isolated murine ovarian preantral follicles

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Summary: The study found that 5-FU can adversely affect the ovarian follicle reserve by reducing the survival of preantral follicles, leading to a significantly lower percentage of normal follicles of all types and impacting the survival of cultured normal primordial follicles.

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