Facile and efficient access to C1-aminosugar derivatives under mild conditions

A facile and efficient synthesis of C1-aminosugar derivatives under catalyst-free conditions is described here. In particular, readily available benzoyl glycosyl bromides react smoothly to give a broad scope of C1-aminosugar derivatives in good yields. The present method proves to be efficient and facile in terms of short reaction time, high yield and the broad substrate scope. (C) 2022 Elsevier Ltd. All rights reserved.

Automated summary

A facile and efficient method for synthesizing C1-aminosugar derivatives under catalyst-free conditions is described. The method utilizes readily available benzoyl glycosyl bromides to smoothly obtain a broad scope of C1-aminosugar derivatives with good yields. It offers the advantages of short reaction time, high yield, and a wide substrate scope.