Ferrocenephosphonates: Copper-Promoted Synthesis and Further Functionalization

Ferrocenephosphonates make up an important class of organometallic derivatives with a wide range of useful applications in organic synthesis and coordination chemistry. Here, an approach to ferro-cenephosphonates based on a copper-promoted Hirao coupling is reported. Further functionalizations based on regioselective deprotolithiation and both Negishi and Suzuki-Miyaura cross-coupling reactions are also described to reach original derivatives.

Automated summary

This article presents a method for the synthesis of ferrocenephosphonates and describes further functionalization through regioselective deprotolithiation and Negishi and Suzuki-Miyaura cross-coupling reactions. These findings provide important insights and foundations for organic synthesis and coordination chemistry.