期刊
INTERNAL MEDICINE
卷 55, 期 9, 页码 1183-1186出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.55.5319
关键词
non-producing multiple myeloma; quadruple cancer; autopsy
We report the case of a 72-year-old man who presented with non-producing multiple myeloma ( MM) with three additional concomitant solid tumors that were identified by postmortem autopsy. The disease was refractory to anti-MM therapy including bortezomib and lenalidomide, and he finally died of bacterial pneumonia with diffuse alveolar damage 8 months after the diagnosis. An autopsy revealed that he was also affected by three other solid cancers, cholangiocellular carcinoma, medullary thyroid cancer and papillary thyroid cancer that were clinically asymptomatic and remained undiagnosed before death. A review of the literature suggests that primary quadruple cancers including MM are extremely rare.
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