期刊
INTERNAL MEDICINE
卷 55, 期 6, 页码 699-702出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.55.5727
关键词
MOG; ADEM; optic neuritis; adult
Acute disseminated encephalomyelitis (ADEM) followed by optic neuritis (ON) has been reported as a distinct phenotype associated with anti-myelin oligodendrocyte protein (MOG) antibody. We herein report the case of a 37-year-old woman who was diagnosed with ADEM at 4 years old of age and who subsequently developed ON followed by recurrent ADEM 33 years after the initial onset. A serum analysis showed anti-MOG antibody positivity. This phenotype has only previously been reported in pediatric cases. Neurologists thus need to be aware that the phenotype may occur in adult patients, in whom it may be assumed to be atypical multiple sclerosis.
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