Magnitude of Blood Pressure Change After Endovascular Therapy and Outcomes: Insight From the BP-TARGET Trial

Review Endocrinology & Metabolism

Review of major trials of acute blood pressure management in stroke

Thompson G. Robinson et al.

Summary: Recent clinical trials on stroke have focused on the impact of acute hypertensive crises and attempts to address acute blood pressure management during the acute stroke period to improve patient prognosis.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2022)

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Article Neuroimaging

Blood pressure reduction and outcome after endovascular therapy: a secondary analysis of the BEST study

Mohammad Anadani et al.

Summary: The reduction in baseline systolic blood pressure following endovascular therapy was not associated with poor functional outcomes. Most of the cohort achieved successful recanalization, with no association between reduced systolic blood pressure and negative outcomes observed.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2021)

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Article Clinical Neurology

Magnitude of blood pressure change and clinical outcomes after thrombectomy in stroke caused by large artery occlusion

Mohammad Anadani et al.

Summary: The study found that an increase in systolic blood pressure after thrombectomy in large artery occlusion stroke patients is associated with poor surgical outcomes. Higher increments in systolic blood pressure were linked to unfavorable outcomes at various time intervals, indicating a potential impact on patient recovery post-surgery.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

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Article Clinical Neurology

Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial

Mikael Mazighi et al.

Summary: This study aimed to evaluate the effect of different systolic blood pressure targets on rates of intraparenchymal hemorrhage in acute ischemic stroke patients after endovascular therapy. The results showed that an intensive systolic blood pressure target did not reduce intraparenchymal hemorrhage rates compared to a standard target. Further research is needed to understand the relationship between blood pressure and outcomes after reperfusion.

LANCET NEUROLOGY (2021)

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Editorial Material Clinical Neurology