A spectroscopic probe for hypochlorous acid detection

A spectroscopic probe CMBT was synthesized and characterized. CMBT showed the specific recognition for HClO based on the turn-on blue fluorescence and naked-eye change from pink to colorless. NMR, IR, HRMS-ESI, and spectral analysis suggested that colorimetric and fluorescent change of CMBT to HClO originated from the conversion of CMBT to starting material coumarin-aldehyde 1 caused by the oxidization of HClO, which was responsible for the fluorescence recovery. The detection limit was calculated to be 1.61 mu M and 6.58 mu M for fluorescence and UV-vis analysis with a range up to 1 mM. HClO's fluorescence detection was successfully achieved in tap and river water samples. The prepared convenient paper test strips showed a distinct color change in varying concentrations of HClO. A multi-input molecular logic circuit was constructed.(c) 2021 Elsevier B.V. All rights reserved.

Automated summary

A spectroscopic probe CMBT was synthesized and characterized. CMBT showed specific recognition for HClO through turn-on blue fluorescence and naked-eye color change. The detection of HClO was successfully achieved in tap and river water samples. In addition, a multi-input molecular logic circuit was constructed.