Sexual dimorphism in functional pain syndromes

Injury-free pain conditions, defined as functional pain syndromes, are more prevalent and more disabling in women. Mechanisms of sexual dimorphism in functional pain are now emerging from preclinical studies, suggesting an opportunity to advance the development of sex-specific therapies that may improve treatment of pain in women.

Automated summary

Injury-free pain conditions, known as functional pain syndromes, are more prevalent and disabling in women. Recent preclinical studies have revealed mechanisms of sexual dimorphism in functional pain, offering an opportunity to develop sex-specific therapies that could enhance pain treatment in women.