相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Primary African Isolates
Julio C. C. Lorenzi et al.
JOURNAL OF VIROLOGY (2021)
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
Ryan S. Roark et al.
SCIENCE (2021)
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations
Frauke Muecksch et al.
IMMUNITY (2021)
Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization
Hannah L. Turner et al.
SCIENCE ADVANCES (2021)
Isolation of single HIV-1 Envelope specific B cells and antibody cloning from immunized rhesus macaques
Zijun Wang et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2020)
Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines
Bartek Nogal et al.
CELL REPORTS (2020)
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
Prabhu S. Arunachalam et al.
NATURE MEDICINE (2020)
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
Christopher O. Barnes et al.
CELL (2020)
HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite
Bartek Nogal et al.
SCIENCE ADVANCES (2020)
Structural and functional evaluation ofde novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens
Aleksandar Antanasijevic et al.
PLOS PATHOGENS (2020)
A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
Zijun Wang et al.
ELIFE (2020)
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
Till Schoofs et al.
IMMUNITY (2019)
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
Amelia Escolano et al.
NATURE (2019)
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization
Rui Kong et al.
CELL (2019)
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
Kwinten Sliepen et al.
NATURE COMMUNICATIONS (2019)
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
Jon M. Steichen et al.
SCIENCE (2019)
Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers
Matthias G. Pauthner et al.
IMMUNITY (2019)
Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells
Yehuda Z. Cohen et al.
JOURNAL OF VIROLOGY (2018)
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
Thomas D. Goddard et al.
PROTEIN SCIENCE (2018)
HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
Peter D. Kwong et al.
IMMUNITY (2018)
Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens
Robert K. Abbott et al.
IMMUNITY (2018)
Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity
Pia Dosenovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers
Lucy Rutten et al.
CELL REPORTS (2018)
Real-space refinement in PHENIX for cryo-EM and crystallography
Pavel V. Afonine et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2018)
Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization
Matteo Bianchi et al.
IMMUNITY (2018)
A fully automatic method yielding initial models from high-resolution cryo-electron microscopy maps
Thomas C. Terwilliger et al.
NATURE METHODS (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov et al.
ELIFE (2018)
Progress toward active or passive HIV-1 vaccination
Amelia Escolano et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
Marit J. van Gils et al.
NATURE MICROBIOLOGY (2017)
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure
Jeong Hyun Lee et al.
IMMUNITY (2017)
The quest for an antibody-based HIV vaccine
Barton F. Haynes et al.
IMMUNOLOGICAL REVIEWS (2017)
Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development
Mattia Bonsignori et al.
IMMUNOLOGICAL REVIEWS (2017)
Identification and specificity of broadly neutralizing antibodies against HIV
Laura E. McCoy et al.
IMMUNOLOGICAL REVIEWS (2017)
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
Max Medina-Ramirez et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging
Wim J. H. Hagen et al.
JOURNAL OF STRUCTURAL BIOLOGY (2017)
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
Ali Punjani et al.
NATURE METHODS (2017)
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
Natalia T. Freund et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains
M. Gordon Joyce et al.
CELL REPORTS (2017)
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies
Haoqing Wang et al.
ELIFE (2017)
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
Mattia Bonsignori et al.
CELL (2016)
Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice
Amelia Escolano et al.
CELL (2016)
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans
Devin Sok et al.
IMMUNITY (2016)
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
Jon M. Steichen et al.
IMMUNITY (2016)
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
Rajeev Gautam et al.
NATURE (2016)
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
Harry B. Gristick et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Visualizing antibody affinity maturation in germinal centers
Jeroen M. J. Tas et al.
SCIENCE (2016)
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
Rui Kong et al.
SCIENCE (2016)
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
Harry B. Gristick et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
Laura E. McCoy et al.
CELL REPORTS (2016)
Structural basis for germline antibody recognition of HIV-1 immunogens
Louise Scharf et al.
ELIFE (2016)
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization
Karl D. Brune et al.
SCIENTIFIC REPORTS (2016)
Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env
Louise Scharf et al.
CELL (2015)
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
Alexis Rohou et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene
Pavel Pugach et al.
JOURNAL OF VIROLOGY (2015)
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
Jeong Hyun Lee et al.
NATURE COMMUNICATIONS (2015)
Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
Feng Gao et al.
CELL (2014)
Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies
Fernando Garces et al.
CELL (2014)
Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy
Anthony P. West et al.
CELL (2014)
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
Masashi Shingai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
Allan deCamp et al.
JOURNAL OF VIROLOGY (2014)
Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
Florian Klein et al.
CELL (2013)
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
Hua-Xin Liao et al.
NATURE (2013)
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Leopold Kong et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Mitigation of variation observed in a peripheral blood mononuclear cell (PBMC) based HIV-1 neutralization assay by donor cell pooling
Lindsay Wieczorek et al.
VIROLOGY (2013)
A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
Rogier W. Sanders et al.
PLOS PATHOGENS (2013)
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
Sjors H. W. Scheres
JOURNAL OF STRUCTURAL BIOLOGY (2012)
Antibody-based protection against HIV infection by vectored immunoprophylaxis
Alejandro B. Balazs et al.
NATURE (2012)
A mouse model for HIV-1 entry
John Pietzsch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin
Bijan Zakeri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
Brian Moldt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Most rhesus macaques infected with the CCR5-tropic SHIVAD8 generate cross-reactive antibodies that neutralize multiple HIV-1 strains
Masashi Shingai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
Hugo Mouquet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center
Tanja A. Schwickert et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
Mattia Bonsignori et al.
JOURNAL OF VIROLOGY (2011)
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
Fabian Sievers et al.
MOLECULAR SYSTEMS BIOLOGY (2011)
Broad neutralization coverage of HIV by multiple highly potent antibodies
Laura M. Walker et al.
NATURE (2011)
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
Johannes F. Scheid et al.
SCIENCE (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
Ann J. Hessell et al.
JOURNAL OF VIROLOGY (2010)
Generation of the Pathogenic R5-Tropic Simian/Human Immunodeficiency Virus SHIVAD8 by Serial Passaging in Rhesus Macaques
Yoshiaki Nishimura et al.
JOURNAL OF VIROLOGY (2010)
Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity
Ron Diskin et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Versatile Virus-Like Particle Carrier for Epitope Based Vaccines
Alain C. Tissot et al.
PLOS ONE (2010)
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
Tongqing Zhou et al.
SCIENCE (2010)
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
Xiaodong Xiao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
Ann J. Hessell et al.
NATURE MEDICINE (2009)
Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
Laura M. Walker et al.
SCIENCE (2009)
Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
Ann J. Hessell et al.
PLOS PATHOGENS (2009)
IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
Xavier Brochet et al.
NUCLEIC ACIDS RESEARCH (2008)
EMAN2: An extensible image processing suite for electron microscopy
Guang Tang et al.
JOURNAL OF STRUCTURAL BIOLOGY (2007)
Visualizing density maps with UCSF Chimera
Thomas D. Goddard et al.
JOURNAL OF STRUCTURAL BIOLOGY (2007)
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in southern Africa
Ming Li et al.
JOURNAL OF VIROLOGY (2006)
Automated electron microscope tomography using robust prediction of specimen movements
DN Mastronarde
JOURNAL OF STRUCTURAL BIOLOGY (2005)
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
A Trkola et al.
NATURE MEDICINE (2005)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Role of BCR affinity in T cell-dependent antibody responses in vivo
TAY Shih et al.
NATURE IMMUNOLOGY (2002)
Short- and long-term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric simian/human immunodeficiency virus
Y Endo et al.
JOURNAL OF VIROLOGY (2000)
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
JR Mascola et al.
NATURE MEDICINE (2000)
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
TW Baba et al.
NATURE MEDICINE (2000)
分享论文
