期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 791, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2021.148152
关键词
Antibiotics; Antibiotic resistance genes (ARGs); Drinking water source; Successive monitoring; Annual increase
资金
- Science and Technology Commission of Shanghai Municipality [20dz1200800]
- National Water Pollution Control and Management Technology Major Projects [2017ZX07402003]
- Shanghai Sailing Program [21YF1409700]
The pollution of antibiotics and antibiotic resistance genes in drinking water source is a global concern. This study revealed an annual increase in total ARG concentration in the studied drinking water source, primarily due to the rise in specific ARG subtypes. Additionally, the variation of antibiotics and ARGs appeared to be related to the water indices.
The extensive pollution of antibiotics and antibiotic resistance genes (ARGs) in drinking water has aroused worldwide concern. Successive monitoring of these pollutants has noteworthy significance for drinking water safety. Accordingly, this study conducted successive monitoring of antibiotics and ARGs from 2015 to 2017 in a drinking water source in East China. The total antibiotic concentration ranged from 19.68 ng/L to 497.00 ng/L, and decreased slightly from 2015 to 2017. Eighteen out of forty-one ARG subtypes showing resistance to six antibiotic classes and one class I integrase gene intI1, were detected in the drinking water source at concentrations ranging from 6.5 x 10(4) copies/mL to 1.6 x 10(6) copies/mL. Importantly, the total ARG concentration increased on an annual basis from 2015 to 2017 with an average annual increment of 0.25 orders of magnitude, which was mainly attributed to the increase in specific ARG subtypes, such as sul1, sul2, sul3, tetA, qnrB, and ermB. Most ARGs was positively correlated with the intI1 genes (r = 0.47-0.55, P < 0.01). Furthermore, the variation of antibiotics and ARGs appeared to be related to the water indices, particularly of the values of COD, BOD5, NO2-N (P < 0.05). This study provides basic data on antibiotic and ARG pollution in the studied drinking water source. Importantly, the findings expound that although the residual antibiotics in this drinking water source decreased slightly from 2015 to 2017, while its biological effect, the antibiotic resistance, increased annually, which give a warning of the antibiotic resistance pollution in the drinking water source. (C) 2021 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据