期刊
SCIENCE
卷 375, 期 6585, 页码 1155-+出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.abm3087
关键词
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资金
- Ivan and Francesca Berkowitz family living laboratory collaboration at the Harvard Medical School
- Clalit Research Institute
- Morris-Singer Fund
Children who are not vaccinated against SARS-CoV-2 can still be protected by vaccinated parents. A study found that having a single vaccinated parent reduced the risk of infection for unvaccinated children by 26.0% and 20.8% in two different periods, while having two vaccinated parents reduced the risk by 71.7% and 58.1%, respectively.
Children not vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may still benefit from vaccines through protection from vaccinated contacts. We estimated the protection provided to children through parental vaccination with the BNT162b2 vaccine. We studied households without prior infection consisting of two parents and unvaccinated children, estimating the effect of parental vaccination on the risk of infection for unvaccinated children. We studied two periods separately-an early period (17 January 2021 to 28 March 2021; Alpha variant, two doses versus no vaccination) and a late period (11 July 2021 to 30 September 2021; Delta variant, booster dose versus two vaccine doses). We found that having a single vaccinated parent was associated with a 26.0 and a 20.8% decreased risk in the early and late periods, respectively, and having two vaccinated parents was associated with a 71.7 and a 58.1% decreased risk, respectively. Thus, parental vaccination confers substantial protection on unvaccinated children in the household.
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