期刊
ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY
卷 62, 期 1, 页码 219-226出版社
EDITURA ACAD ROMANE
DOI: 10.47162/RJME.62.1.21
关键词
experimental model; inflammation; periodontal disease; ligature; Calcium Fructoborate; Boric Acid
资金
- Romanian Ministry of Education and Research, CNCS-UEFISCDI [PN-III-P1-1.1-PD-2019-0214]
The study showed that using boron-containing hydrogels for periodontitis treatment has a positive effect in reducing inflammation levels in oral tissues. However, more scientifically proven information is needed to achieve the desired biological responses in various clinical situations.
Periodontitis is a disease that affects a wide group of people, and there has been an increased interest in the research of finding useful materials that help reduce inflammation and the further loss of tissue. In this study, we have tested a boron-containing compound (BCC) Calcium Fructoborate (CaFB) and Boric Acid (BA) hydrogels on the gingival level on Wistar rats. First, we have induced the periodontal disease at the lower incisors, we have applied the hydrogels and after a week, we have euthanized the rats. Next, the oral soft tissue reaction was clinically and then histologically investigated. Our study has shown good clinical response of the oral tissue, and we have noticed lower levels of inflammation on the experimental groups treated with the BCCs hydrogels. Despite the generally good response of the biological structures to the presence of BA and CaFB on periodontal level, more scientifically proved information is needed to obtain the desired biological responses in all clinical situations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据