4.6 Review

Circulating tumor DNA: a noninvasive biomarker for tracking ovarian cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients

Lindsey M. Charo et al.

Summary: The molecular characterization of gynecologic cancers through ctDNA analysis plays a vital role in determining prognosis and guiding personalized therapy. This study found that higher ctDNA mutation frequency is associated with poor overall survival, while therapy tailored to ctDNA alterations leads to improved outcomes. The concordance between tissue and ctDNA genomic results remains high, demonstrating the potential utility of ctDNA in individualizing cancer therapy for gynecologic cancer patients.

MOLECULAR ONCOLOGY (2021)

Article Oncology

A Novel, Personalized Drug-Screening System for Platinum-Resistant Ovarian Cancer Patients: A Preliminary Clinical Report

Yunke Huang et al.

Summary: This study established a personalized and sensitive drug-screening system for platinum-resistant ovarian cancer patients, identifying potentially effective drugs for the patients using mini-PDX models. The clinical-benefit rate was 75.0%, demonstrating the efficacy of the personalized drug-selection system.

CANCER MANAGEMENT AND RESEARCH (2021)

Article Oncology

Genome-wide Copy-number Alterations in Circulating Tumor DNA as a Novel Biomarker for Patients with High-grade Serous Ovarian Cancer

Lara Paracchini et al.

Summary: TF in plasma serves as an independent prognostic marker for disease progression and relapse in HGS-EOC patients. After platinum-based treatment, ctDNA analysis shows changes in genomic amplification patterns, with serially collected ctDNA samples' TF outperforming CA-125 in predicting disease progression.

CLINICAL CANCER RESEARCH (2021)

Review Pharmacology & Pharmacy

Circulating tumor DNA as an early cancer detection tool

Andrea Campos-Carrillo et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Article Oncology

Biomarkers and Strategies for Early Detection of Ovarian Cancer

Robert C. Bast et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2020)

Article Biotechnology & Applied Microbiology

A Study of hTERT Promoter Methylation in Circulating Tumour DNAs of Patients with Ovarian Magnificent Tumour

Songyi Li et al.

ONCOTARGETS AND THERAPY (2020)

Article Oncology

Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage

Lauren C. Peres et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

Article Oncology

Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage

Lauren C. Peres et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

Article Multidisciplinary Sciences

Genome-wide cell-free DNA fragmentation in patients with cancer

Stephen Cristiano et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

Dominic G. Rothwell et al.

NATURE MEDICINE (2019)

Article Oncology

Ovarian Cancer Statistics, 2018

Lindsey A. Torre et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

Article Oncology

Cancer Statistics, 2018

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

Article Oncology

Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

Rebecca C. Arend et al.

MOLECULAR CANCER RESEARCH (2018)

Article Multidisciplinary Sciences

Detection and localization of surgically resectable cancers with a multi-analyte blood test

Joshua D. Cohen et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma

S. Manier et al.

NATURE COMMUNICATIONS (2018)

Article Medicine, General & Internal

Utility of circulating tumor DNA in cancer diagnostics with emphasis on early detection

Clare Fiala et al.

BMC MEDICINE (2018)

Article Cell Biology

Enhanced detection of circulating tumor DNA by fragment size analysis

Florent Mouliere et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Article Oncology

Autoantibodies against HSF1 and CCDC155 as Biomarkers of Early-Stage, High-Grade Serous Ovarian Cancer

Amy L. Wilson et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2018)

Review Biochemistry & Molecular Biology

The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer

Dimakatso Alice Senthebane et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Multidisciplinary Sciences

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Christopher Abbosh et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Iron addiction: a novel therapeutic target in ovarian cancer

D. Basuli et al.

ONCOGENE (2017)

Article Cell Biology

Direct detection of early-stage cancers using circulating tumor DNA

Jillian Phallen et al.

SCIENCE TRANSLATIONAL MEDICINE (2017)

Article Multidisciplinary Sciences

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

Viktor A. Adalsteinsson et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Assessment of circulating copy number variant detection for cancer screening

Bhuvan Molparia et al.

PLOS ONE (2017)

Article Biotechnology & Applied Microbiology

ReMixT: clone-specific genomic structure estimation in cancer

Andrew W. McPherson et al.

GENOME BIOLOGY (2017)

Review Oncology

Liquid biopsies come of age: towards implementation of circulating tumour DNA

Jonathan C. M. Wan et al.

NATURE REVIEWS CANCER (2017)

Review Cell Biology

Circulating-tumor DNA as an early detection and diagnostic tool

Timothy M. Butler et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2017)

Article Oncology

Clinical Use of Cancer Biomarkers in Epithelial Ovarian Cancer Updated Guidelines From the European Group on Tumor Markers

Gyorgy Soletormos et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2016)

Article Multidisciplinary Sciences

Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers

Faye R. Harris et al.

SCIENTIFIC REPORTS (2016)

Editorial Material Pathology

Potential clinical utility of ultrasensitive circulating tumor DNA detection with CAPP-Seq

Scott V. Bratman et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2015)

Article Medicine, General & Internal

Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

Diana W. Bianchi et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

Article Multidisciplinary Sciences

Whole-genome characterization of chemoresistant ovarian cancer

Ann-Marie Patch et al.

NATURE (2015)

Article Multidisciplinary Sciences

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments

Kun Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Editorial Material Genetics & Heredity

Exome Sequencing: Current and Future Perspectives

Amanda Warr et al.

G3-GENES GENOMES GENETICS (2015)

Article Oncology

Liquid Biopsies: Genotyping Circulating Tumor DNA

Luis A. Diaz et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

Article Multidisciplinary Sciences

Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma

Daniel Klevebring et al.

PLOS ONE (2014)

Article Cell Biology

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Chetan Bettegowda et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Medicine, General & Internal

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

Sarah-Jane Dawson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Multidisciplinary Sciences

Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

K. C. Allen Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Cell Biology

Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers

Isaac Kinde et al.

SCIENCE TRANSLATIONAL MEDICINE (2013)

Article Biotechnology & Applied Microbiology

Characterizing and measuring bias in sequence data

Michael G. Ross et al.

GENOME BIOLOGY (2013)

Article Oncology

Stem Cell Pathways Contribute to Clinical Chemoresistance in Ovarian Cancer

Adam D. Steg et al.

CLINICAL CANCER RESEARCH (2012)

Article Obstetrics & Gynecology

Immunohistochemical Localization of HE4 in Benign, Borderline, and Malignant Lesions of the Ovary

Penelope Georgakopoulos et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY (2012)

Article Multidisciplinary Sciences

Detection and quantification of rare mutations with massively parallel sequencing

Isaac Kinde et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Editorial Material Oncology

CA 125 and the Detection of Recurrent Ovarian Cancer

Robert C. Bast

CANCER (2010)

Review Oncology

The biology of ovarian cancer: new opportunities for translation

Robert C. Bast et al.

NATURE REVIEWS CANCER (2009)

Article Biochemistry & Molecular Biology

Circulating mutant DNA to assess tumor dynamics

Frank Diehl et al.

NATURE MEDICINE (2008)