Trends in lipase immobilization: Bibliometric review and patent analysis

Enzymes have great industrial potential as biocatalysts, particularly lipases, which have attracted much attention for their extensive applications. As the use of enzymes becomes more widespread, a variety of enzyme immobilization methods are being developed for enhanced performance. This review provides a bibliometric and patent analysis of lipase immobilization techniques. Scientific papers and patents were searched in Web of Science and World Intellectual Property Organization databases, respectively. The results showed that immobilized lipases are being extensively used for the production of flavor esters and biodiesel. China, India, and Brazil, as well as institutions related to these countries, stand out as the most academically productive in terms of lipase immobilization research. It was also found that many researchers and journals focused exclusively on this field. Patent analysis revealed a large number of filed patents, indicative of the industrial potential of immobilized lipases. These findings underscore the importance of research on lipase immobilization for a diversity of applications.

Automated summary

Enzymes, particularly lipases, have great industrial potential and are being extensively used for flavor ester and biodiesel production through immobilization techniques. China, India, Brazil, and related institutions are academically productive in lipase immobilization research, with many researchers and journals focusing exclusively on this field. The large number of filed patents for immobilized lipases underscores their industrial potential for diverse applications.