Nanostructure-mediated glucose oxidase biofunctionalization for monitoring gestational diabetes

Gestational diabetes is the condition with an elevated blood glucose level during the pregnancy period. Approximately 10 % of women have been affected by gestational diabetes in USA every year. Babies of pregnant mothers are with diabetes have increased risk of developing type-2 diabetes and obesity in their later life. In addition, uncontrolled diabetes causes the death to infant either before or immediate after the birth. It is mandatory to monitor the condition of diabetes during the pregnancy period for a healthy delivery. Researches are developing various simple biosensing methods to monitor the glucose level using glucose oxidase. Recently nanomaterials are focused by researchers to develop high-performance glucose sensors due to its high surface area, biocompatibility, higher sensitivity and selectivity. Nanomaterials are proved for improving the detection with glucose oxidase by various sensors to identify gestational diabetes. This review is discussed on sensing methods development for gestational diabetes and the incorporation of different nanomaterial in monitoring the glucose level during the pregnancy period.

Automated summary

Gestational diabetes refers to elevated blood glucose levels during pregnancy, affecting approximately 10% of women in the USA annually. Researchers are focusing on using nanomaterials to develop high-performance glucose sensors for improved detection of gestational diabetes.