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Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat
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Markus Hoffmann et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
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Ruochen Zang et al.
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Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
James Brett Case et al.
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Sanchit Seth et al.
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Wen Cui et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19
Jonathan H. Shrimp et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)
Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2
Vishnu C. Damalanka et al.
FUTURE MEDICINAL CHEMISTRY (2019)
Cell surface-anchored serine proteases in cancer progression and metastasis
Carly E. Martin et al.
CANCER AND METASTASIS REVIEWS (2019)
Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology
Vishnu C. Damalanka et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin
Vishnu C. Damalanka et al.
MEDCHEMCOMM (2019)
The role of type II transmembrane serine protease-mediated signaling in cancer
Lauren M. Tanabe et al.
FEBS JOURNAL (2017)
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Benjamin Y. Owusu et al.
ONCOTARGET (2017)
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Benjamin Yaw Owusu et al.
CANCERS (2017)
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Sam L. Ivry et al.
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-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer
Zhenfu Han et al.
CHEMMEDCHEM (2016)
Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism
Jung-Eun Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets
Francisco M. Franco et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics
Wolfgang Garten et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2015)
The Host Protease TMPRSS2 Plays a Major Role in In Vivo Replication of Emerging H7N9 and Seasonal Influenza Viruses
Kouji Sakai et al.
JOURNAL OF VIROLOGY (2014)
Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer
Zhenfu Han et al.
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Jared M. Lucas et al.
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Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
Graham Simmons et al.
ANTIVIRAL RESEARCH (2013)
Correlating Cell Line Studies With Tissue Distribution of DPP4/TMPRSS2 and Human Biological Samples May Better Define the Viral Tropism of MERS-CoV
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Joanna Baron et al.
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Matriptase Proteolytically Activates Influenza Virus and Promotes Multicycle Replication in the Human Airway Epithelium
Alexandre Beaulieu et al.
JOURNAL OF VIROLOGY (2013)
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Masako Abe et al.
JOURNAL OF VIROLOGY (2013)
Effect of Signal Peptide on Stability and Folding of Escherichia coli Thioredoxin
Pranveer Singh et al.
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A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus
Dong-Hoon Chung et al.
VIROLOGY JOURNAL (2013)
Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice
Bastian Hatesuer et al.
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Cleavage Activation of the Human-Adapted Influenza Virus Subtypes by Matriptase Reveals both Subtype and Strain Specificities
Brian S. Hamilton et al.
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Global identification of peptidase specificity by multiplex substrate profiling
Anthony J. O'Donoghue et al.
NATURE METHODS (2012)
Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts
Stephanie Bertram et al.
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Type II Transmembrane Serine Proteases
Thomas H. Bugge et al.
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Enzymatic assembly of DNA molecules up to several hundred kilobases
Daniel G. Gibson et al.
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Type II transmembrane serine proteases in cancer and viral infections
So-Young Choi et al.
TRENDS IN MOLECULAR MEDICINE (2009)
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma
J. M. Lucas et al.
JOURNAL OF PATHOLOGY (2008)
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
Eva Böttcher et al.
JOURNAL OF VIROLOGY (2006)
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
S Herter et al.
BIOCHEMICAL JOURNAL (2005)
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
K Chandran et al.
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Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
T Takeuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)