相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
Florian Beaumatin et al.
MOLECULAR CELL (2019)
Nutrient acquisition strategies of mammalian cells
Wilhelm Palm et al.
NATURE (2017)
Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes
Monther Abu-Remaileh et al.
SCIENCE (2017)
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient
Gregory A. Wyant et al.
CELL (2017)
METABOLISM Sestrin2 is a leucine sensor for the mTORC1 pathway
Rachel L. Wolfson et al.
SCIENCE (2016)
Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
Sonja Aits et al.
AUTOPHAGY (2015)
The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
Wilhelm Palm et al.
CELL (2015)
Autophagy in cellular metabolism and cancer
Xuejun Jiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Inducible in vivo genome editing with CRISPR-Cas9
Lukas E. Dow et al.
NATURE BIOTECHNOLOGY (2015)
LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation
Ruth Milkereit et al.
NATURE COMMUNICATIONS (2015)
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey et al.
NATURE (2015)
Autophagy regulation by nutrient signaling
Ryan C. Russell et al.
CELL RESEARCH (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
Rag GTPases are cardioprotective by regulating lysosomal function
Young Chul Kim et al.
NATURE COMMUNICATIONS (2014)
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Cosimo Commisso et al.
NATURE (2013)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
Liron Bar-Peled et al.
SCIENCE (2013)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
Shomit Sengupta et al.
MOLECULAR CELL (2010)
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes
Shigeyki Nada et al.
EMBO JOURNAL (2009)
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
Carson C. Thoreen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
Urmi Bandyopadhyay et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
J Debnath et al.
METHODS (2003)
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
K Inoki et al.
NATURE CELL BIOLOGY (2002)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)