期刊
POLYMER CHEMISTRY
卷 13, 期 5, 页码 600-612出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1py01529j
关键词
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资金
- CONACYT [548662]
- French National Agency for research (ANR) [ANR-17-CE07-0039-01]
New macromolecular engineering approaches were developed to prepare star-like polypeptoids through ring-opening polymerization. Evaluation of their cytotoxicity on HepG2 human cell line and screening against a variety of Gram-positive and Gram-negative bacteria identified several compounds with both good and selective antimicrobial activity.
We developed new macromolecular engineering approaches enabling the preparation of star-like polypeptoids by ring-opening polymerization. Parallely to the evaluation of their cytotoxicity of the HepG2 human cell line, their screening toward a wide variety of Gram-positive and Gram-negative bacteria higlighted several compounds showing not only good but also selective antimicrobial activity.
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