期刊
POLYMER BULLETIN
卷 80, 期 2, 页码 1519-1530出版社
SPRINGER
DOI: 10.1007/s00289-022-04109-1
关键词
Electrospinning; Substrate temperature; Gelatin; Nanofibers
The substrate temperature was investigated to broaden the applicability of controlling the morphology of polymeric fibers produced during the electrospinning process. A gelatin polymer was used as an example to obtain beads-free gelatin fibers by fixing the main electrospinning parameters. Heating the substrate at 50 degrees C resulted in a significant decrease in fiber diameter, while increasing substrate temperatures from 75 to 100 degrees C showed stability of the diameter with a significant variation in their diameter distribution.
The substrate temperature was investigated to broaden the applicability of controlling the morphology of polymeric fibers produced during the electrospinning process. A laboratory electrospinning setup was designed using a substrate heated in a temperature range of 25 degrees C to 100 degrees C. A gelatin polymer was used as an example to obtain beads-free gelatin fibers by fixing the main electrospinning parameters. Based on XRD, FTIR, and DSC techniques, the electrospun gelatin fibers did not show any change in their chemical composition up to 100 degrees C. Heating the substrate at 50 degrees C may be the best selection factor to obtain gelatin fibers; the fiber diameters experienced a significant decrease from 680 +/- 140 nm to 420 +/- 120 nm with increasing substrate temperature from 25 to 50 degrees C, respectively. They showed stability of the diameter at 380 +/- 130 nm and 390 +/- 130 nm when increasing substrate temperatures from 75 to 100 degrees C, respectively, with a significant variation in their diameter distribution. Therefore, this ability to control the electrospinning process using a heated substrate makes it promising for fabricating electrospun beads-free fibers of biopolymers such as gelatin for tissue engineering and drug delivery carriers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据