4.6 Article

Implant-Based Reconstruction following Mastectomy in Patients Who Have Had a Previous Breast Augmentation: Lessons from the National Multicenter Implant Breast Reconstruction Evaluation Study

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PLASTIC AND RECONSTRUCTIVE SURGERY
卷 149, 期 2, 页码 324-337

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PRS.0000000000008713

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资金

  1. National Institute for Health Research, Research for Patient Benefit Programme grant [PB-PG-0214-33065]
  2. Association of Breast Surgery
  3. British Association of Plastic Reconstructive and Aesthetic Surgeons
  4. National Institute for Health Research Clinician Scientist [CS2016-16-019]
  5. Medical Research Council ConDuCT-II Collaboration and innovation for Difficult and Complex randomized controlled Trials In Invasive procedures) Hub for Trials Methodology Research [MR/K025643/1]
  6. National Institute for Health Research Biomedical Research Centre at University Hospitals Bristol National Health Service Foundation Trust
  7. University of Bristol

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This study examined the clinical and patient-reported outcomes of women undergoing immediate implant-based breast reconstruction following previous augmentation. The results showed that the outcomes of this approach were similar to those of patients without cosmetic implants.
Background: Breast augmentation is the most commonly performed cosmetic procedure, and increasingly women ill this group present with breast cancer or request risk-reducing surgery. but their optimal management is unclear. The authors explored the clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation and compared these with outcomes of patients who had not had cosmetic implants in the Implant Breast Reconstruction Evaluation (iBRA) Study. Methods: Patients undergoing immediate implant-based breast reconstruction were prospectively recruited horn breast and plastic surgical units across the United Kingdom. Demographic, operative, and oncologic data, and information regarding complications within 3 postoperative mouths were collected. Patient-reported outcomes at 18 months were assessed using the BREAST-Q. The clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction with and without previous breast augmentation were compared. Results: A total of 2108 women were included in the iRRA Study, of whom 49 had undergone a previous augmentation.Women in the augmentation group were younger (median age, 45 years versus 50 years; p = 0,01), had a lower body mass index (22.8 kg/m(2) versus 24.9 kg/m(2); p < 0.01), and had smaller tumors (15 min versus 25 min; p= 0.01) than patients without augmentation. No differences were seen in operative technique between the groups. Complications at 3 months were similar in both groups and there were no significant differences patient-reported outcomes at 18 months. Conclusions: The clinical and patient-reported Outcomes of patients under-going immediate implant-based breast reconstruction following previous augmentation are consistent with those observed in die wider iBRA Study cohort, supporting the safety of this approach.

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