4.5 Article

Upregulation of heat-shock protein HSP-70 and glutamate transporter-1/ glutamine synthetase in the striatum and hippocampus in haloperidol-induced dopamine-supersensitivity-state rats

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Accumbens D2-MSN hyperactivity drives antipsychotic-induced behavioral supersensitivity

Anna Kruyer et al.

Summary: Antipsychotic-induced dopamine supersensitivity is a problematic consequence of long-term antipsychotic treatment, characterized by motor abnormalities, refractory symptoms, and rebound psychosis. This phenomenon is associated with long-lasting synaptic plasticity and hyperexcitability in a subpopulation of D2 receptor-expressing neurons, leading to behavioral endophenotypes of treatment resistance and substance use disorder. Chemogenetic restoration of inhibitory postsynaptic currents may offer a novel therapeutic direction for preventing antipsychotic-induced supersensitivity.

MOLECULAR PSYCHIATRY (2021)

Review Neurosciences

Antipsychotic-evoked dopamine supersensitivity

Alice Servonnet et al.

NEUROPHARMACOLOGY (2020)

Review Psychiatry

Dopamine D2 up-regulation in psychosis patients after antipsychotic drug treatment

Ilse A. Thompson et al.

CURRENT OPINION IN PSYCHIATRY (2020)

Review Pharmacology & Pharmacy

Hippocampal Hyperactivity as a Druggable Circuit-Level Origin of Aberrant Salience in Schizophrenia

Dennis Kaetzel et al.

FRONTIERS IN PHARMACOLOGY (2020)

Article Psychiatry

Antipsychotic-Induced Dopamine Supersensitivity Psychosis: Pharmacology, Criteria, and Therapy

Guy Chouinard et al.

PSYCHOTHERAPY AND PSYCHOSOMATICS (2017)

Review Pharmacology & Pharmacy

Targeting of NMDA receptors in new treatments for schizophrenia

Kenji Hashimoto

EXPERT OPINION ON THERAPEUTIC TARGETS (2014)

Review Clinical Neurology

Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders

Kenji Hashimoto et al.

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2013)

Article Veterinary Sciences

Nucleus Accumbens Invulnerability to Methamphetamine Neurotoxicity

Donald M. Kuhn et al.

ILAR JOURNAL (2011)

Review Psychiatry

The Hippocampal Formation in Schizophrenia

Carol A. Tamminga et al.

AMERICAN JOURNAL OF PSYCHIATRY (2010)

Article Multidisciplinary Sciences

Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice

Y Morishima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Neurosciences

Fluorocitrate-mediated astroglial dysfunction causes seizures

JO Willoughby et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Pharmacology & Pharmacy

Long-term effects of olanzapine, risperidone, and quetiapine on ionotropic glutamate receptor types: Implications for antipsychotic drug treatment

FI Tarazi et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)

Article Pharmacology & Pharmacy

Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: A suggested solution based on in vivo occupancy

S Kapur et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)