期刊
PATTERN RECOGNITION
卷 124, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.patcog.2021.108434
关键词
Brain tumor segmentation; Deep learning; Dual-path model; Magnetic resonance imaging; Multi-modal images
资金
- Natural Science Foundations of China [61801202]
This paper proposes a dual-path network based on multi-modal feature fusion to address the issue of tumor segmentation. The network effectively combines different kernel methods, reduces overlap frequency and vanishing gradient, and establishes a dual-path model to enhance segmentation accuracy.
Because of the tumor with infiltrative growth, the glioma boundary is usually fused with the brain tissue, which leads to the failure of accurately segmenting the brain tumor structure through single-modal images. The multi-modal ones are relatively complemented to the inherent heterogeneity and external boundary, which provide complementary features and outlines. Besides, it can retain the structural characteristics of brain diseases from multi angles. However, due to the particularity of multi-modal medical image sampling that increases uneven data density and dense structural vascular tumor mitosis, the glioma may have atypical boundary fuzzy and more noise. To solve this problem, in this paper, the dual path network based on multi-modal feature fusion (MFF-DNet) is proposed. Firstly, the proposed network uses different kernels multiplexing methods to realize the combination of the large-scale perceptual domain and the non-linear mapping features, which effectively enhances the coherence of information flow. Then, the over-lapping frequency and the vanishing gradient phenomenon are reduced by the residual connection and the dense connection, which alleviate the mutual influence of multi-modal channels. Finally, a dual-path model based on the DenseNet network and the feature pyramid networks (FPN) is established to realize the fusion of low-level, middle-level, and high-level features. Besides, it increases the diversification of glioma non-linear structural features and improves the segmentation precision. A large number of ablation experiments show the effectiveness of the proposed model. The precision of the whole brain tumor and the core tumor can reach 0.92 and 0.90, respectively.(c) 2021 Elsevier Ltd. All rights reserved.
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