Three-Dimensional Heterocycles by 5-exo-dig Cyclizations of S-Methyl-N-ynonylsulfoximines

Upon treatment with Cs2CO3, S-methyl-N-ynonylsulfoximines undergo 5-exo-dig cyclizations to give three-dimensional heterocycles. The reactions proceed at ambient temperature with a wide range of substrates affording the corresponding products in good to excellent yields.

Automated summary

Treatment with Cs2CO3 allows S-methyl-N-ynonylsulfoximines to undergo 5-exo-dig cyclizations to form three-dimensional heterocycles. The reactions proceed at ambient temperature with a wide range of substrates, resulting in good to excellent yields of the corresponding products.