期刊
ORGANIC LETTERS
卷 23, 期 21, 页码 8634-8639出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c03343
关键词
-
资金
- DST, SERB, Govt. of India [EMR/2014/000469]
- SERB [CRG/2020/001233]
- CSIR
- SVMCM
This method enables a metal-free, visible-light- and triphenylphosphine-mediated intermolecular reductive amination between nitroarenes and boronic acids at ambient temperature without any photocatalyst. Mechanistically, a slow reduction of nitroarenes to a nitroso and, finally, a nitrene intermediate occurs that leads to the amination product with concomitant 1,2-aryl/alkyl migration from a boronate complex. A wide range of nitroarenes underwent C-N coupling with aryl/alkylboronic acids providing high yields.
We present here a metal- free, visible- light- and triphenylphosphine-mediated intermolecular, reductive amination between nitroarenes and boronic acids at ambient temperature without any photocatalyst. Mechanistically, a slow reduction of nitroarenes to a nitroso and, finally, a nitrene intermediate occurs that leads to the amination product with concomitant 1,2-aryl/-alkyl migration from a boronate complex. A wide range of nitroarenes underwent C-N coupling with aryl-/alkylboronic acids providing high yields.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据