期刊
ORGANIC LETTERS
卷 24, 期 2, 页码 686-691出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c04079
关键词
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资金
- Engineering and Physical Sciences Research Council
- Syngenta [EP/L016419/1]
- AstraZeneca [EP/V519522/1]
- CRITICAT Centre for Doctoral Training
- Heriot-Watt University
A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed, which does not require metals, light, or catalysts, making the protocol operationally simple and more sustainable.
A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.
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