4.8 Article

Synthesis of N-Fused Triazole-Piperazine-Quinazolinones via One-Pot Tandem Click Reaction and Cross-Dehydrogenative Coupling

期刊

ORGANIC LETTERS
卷 23, 期 24, 页码 9365-9370

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c03435

关键词

-

资金

  1. DOP, MOCF, Govt. of India

向作者/读者索取更多资源

A one-pot protocol for synthesizing tetracyclic triazole-piperazine-quinazolinone-fused N-heterocyclic scaffolds is reported, utilizing tandem click and cross-dehydrogentive coupling reactions with high atom economy. The method is highly functional group tolerable and has a broad substrate scope, with some derivatives showing strong white solid-state fluorescence.
Herein, a one-pot protocol to synthesize tetracyclic triazole-piperazine-quinazolinone-fused N-heterocyclic scaffolds is reported. In this strategy, a tandem approach of two highly efficient synthetic reactions, click and cross-dehydrogentive coupling reactions, with high atom economy were employed to obtain the target N-fused scaffolds. Being highly functional group tolerable, this method has broad substrate scope. Interestingly, some of these derivatives showed strong white solid-state fluorescence.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据