The possible benefits of vitamin D in COVID-19

Molecular studies have demonstrated the importance of the exacerbated immune response to SARS-CoV-2 infection, called the cytokine storm, in more severe COVID-19. The pathophysiology is complex and involves several homeostatic factors; among them, a deficit of vitamin D draws attention because of its high frequency in the population. Some evidence suggests that people with low serum vitamin D levels have worse outcomes, often requiring intensive care. This review analyzed the studies available in the global literature addressing the benefits of vitamin D in COVID-19, relating serum levels to the severity of the disease, and indicating vitamin D as a possible prophylactic and therapy in infection. (c) 2021 Elsevier Inc. All rights reserved.

Automated summary

Research has shown that vitamin D may have benefits in COVID-19, with low serum levels of vitamin D being associated with disease severity and potentially serving as a possible prophylactic and treatment for infection.