期刊
NUCLEIC ACIDS RESEARCH
卷 50, 期 D1, 页码 D480-D487出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkab1082
关键词
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资金
- Italian Ministry of University and Research (MIUR) [2017483NH8]
- European Union's Horizon 2020 [778247]
- European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie [842490, 101028908]
- Tempus Public Foundation [158534]
- NRDI Office of the Hungarian government [FK128133]
- National Agency for the Promotion of Science and Technology (ANPCyT) [PICT-2017-1924, PICT-2018-3457]
- Spanish Ministry of Science and Innovation [FPU17/01157]
- Swedish Research Council for Natural Science [VR-2016-06301]
- Swedish E-science Research Center
- National Human Genome Research Institute [U41 HG02273]
- CNRS
- Infectiopole Sud post-doctoral fellowship
- ELIXIR CZ Research Infrastructure [LM2018131]
- Ministry of Education, Science, and Technological Development of the Republic of Serbia
- Universidad Nacional de Quilmes [PUNQ-2019-1309/19]
- Hungarian Scientific Research Fund (OTKA) [K124670, K131702, K129164, K139284]
- VUB Spearhead grant [SRP51, 2019-24]
- ElixirGR [MIS 5002780]
- National Research Council (CONICET) of Argentina
- Cancer Research UK Senior Cancer Research Fellowship [C68484/A28159]
- University of Cyprus
- European Union's Horizon 2020 research and innovation programme [778247, 952334]
- Marie Curie Actions (MSCA) [101028908, 842490] Funding Source: Marie Curie Actions (MSCA)
- Swedish Research Council [2016-06301] Funding Source: Swedish Research Council
The latest update of DisProt version 9 includes a restyled web interface, refactored IDPO, improvements in curation process, and around 30% content growth. The newly implemented reviewing process and curator training aim to provide higher quality and more consistent annotations. Integration with APICURON and adoption of MIADE standard, along with collaborations with GO and ECO consortia and support from ELIXIR infrastructure, enhance interoperability.
The Database of Intrinsically Disordered Proteins (DisProt, URL: https://disprot.org) is the major repository of manually curated annotations of intrinsically disordered proteins and regions from the literature. We report here recent updates of DisProt version 9, including a restyled web interface, refactored Intrinsically Disordered Proteins Ontology (IDPO), improvements in the curation process and significant content growth of around 30%. Higher quality and consistency of annotations is provided by a newly implemented reviewing process and training of curators. The increased curation capacity is fostered by the integration of DisProt with APICURON, a dedicated resource for the proper attribution and recognition of biocuration efforts. Better interoperability is provided through the adoption of the Minimum Information About Disorder (MIADE) standard, an active collaboration with the Gene Ontology (GO) and Evidence and Conclusion Ontology (ECO) consortia and the support of the ELIXIR infrastructure.
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